WormBase Tree Display for Variation: WBVar00242713

WBVar00242713 Name: Public_name: sc108
    Other_name: C01B12.1.1:c.232C>T
      CE07789:p.Arg78Cys
    HGVSg: CHROMOSOME_II:g.23630C>T
  Sequence_details: SMap: S_parent: Sequence: C01B12
    Flanking_sequences: gatggaccacacctattccatcgtcagaag gtcaatactcttcaccaaacccaccagctg
    Mapping_target: C01B12
    Type_of_mutation: Substitution: c t
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00003807
    Laboratory: BE
    Status: Live
  Affects: Gene: WBGene00005017
    Transcript: C01B12.1.1 (12)
    Interactor: WBInteraction000052488
      WBInteraction000052559
      WBInteraction000052561
      WBInteraction000052562
      WBInteraction000052574
      WBInteraction000537324
  Genetics: Interpolated_map_position: II -18.0003
  Description: Phenotype: WBPhenotype:0000502 Paper_evidence: WBPaper00000906
        Curator_confirmed: WBPerson712
        Dominant: Paper_evidence: WBPaper00000906
          Curator_confirmed: WBPerson712
      WBPhenotype:0000519 Paper_evidence: WBPaper00033444
        Curator_confirmed: WBPerson2021
        Remark: Mutant strains tested showed altered fitness compared to wild type when exposed to different bacterial environments such as E. coli, M. luteus, and Pseudomonas sp.and B. megaterium Paper_evidence: WBPaper00033444
            Curator_confirmed: WBPerson2021
      WBPhenotype:0000583 Paper_evidence: WBPaper00005747
        Curator_confirmed: WBPerson2987
        Remark: Authors report "medium dpy" (Table 1) Paper_evidence: WBPaper00005747
            Curator_confirmed: WBPerson2987
        Phenotype_assay: Genotype: kaIs12 [col-19::gfp] Paper_evidence: WBPaper00005747
              Curator_confirmed: WBPerson2987
      WBPhenotype:0000961 Paper_evidence: WBPaper00005747
        Curator_confirmed: WBPerson2987
        Remark: Table 1 Paper_evidence: WBPaper00005747
            Curator_confirmed: WBPerson2987
        Phenotype_assay: Genotype: kaIs12 [col-19::gfp] Paper_evidence: WBPaper00005747
              Curator_confirmed: WBPerson2987
      WBPhenotype:0001412 Paper_evidence: WBPaper00005747
        Curator_confirmed: WBPerson2987
        Remark: Authors report "severe disruption with branching" (Table 1) Paper_evidence: WBPaper00005747
            Curator_confirmed: WBPerson2987
        Phenotype_assay: Genotype: kaIs12 [col-19::gfp] Paper_evidence: WBPaper00005747
              Curator_confirmed: WBPerson2987
      WBPhenotype:0001517 Paper_evidence: WBPaper00005747
        Curator_confirmed: WBPerson2987
        Remark: Authors report "severe disruption" (Table 1) Paper_evidence: WBPaper00005747
            Curator_confirmed: WBPerson2987
        Phenotype_assay: Genotype: kaIs12 [col-19::gfp] Paper_evidence: WBPaper00005747
              Curator_confirmed: WBPerson2987
  Reference: WBPaper00005747
    WBPaper00033444
    WBPaper00000906
    WBPaper00032171
  Remark: Manually curated Gene associations preserved as a text remark so that VEP is the canonical predictor of consequence: WBGene00005017 Missense 78 R to C
  Method: Substitution_allele