WormBase Tree Display for Variation: WBVar00241506

WBVar00241506 Name: Public_name: rh18
  Sequence_details: SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00004518
      WBStrain00004680
    Laboratory: NJ
    Status: Live
  Affects: Gene: WBGene00001086
    Interactor: WBInteraction000052336
  Genetics: Mapping_data: In_2_point: 1612
      In_multi_point: 865
  Description: Phenotype: WBPhenotype:0000032 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: near lethal like Dpy-26 Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Maternal: With_maternal_effect: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000066 Paper_evidence: WBPaper00001011
        Curator_confirmed: WBPerson712
        Maternal: With_maternal_effect: Paper_evidence: WBPaper00001011
            Curator_confirmed: WBPerson712
      WBPhenotype:0000583 Paper_evidence: WBPaper00001011
        Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: Escapers are dumpy. Paper_evidence: WBPaper00001011
            Curator_confirmed: WBPerson712
          XX phenotype is zygotic weak dumpy maternal effect dumpy Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Maternal: With_maternal_effect: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Ease_of_scoring: ES2_Difficult_to_score: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000718 Paper_evidence: WBPaper00001011
        Curator_confirmed: WBPerson712
        Remark: As determined by the penetrance of the lin-14(n179) mutant phenotype, based on the [# mutant seam cell nuclei (undivided seam cell nuclei + nuclei that generated precocious alae)/ total # seam cell nuclei] animals after the L3 molt. Paper_evidence: WBPaper00001011
            Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: Animals were maintained at 24C for two to three generations to obtain enough animals to score. Nomarski optics were used to follow the fates of the midbody seam cell nuclei of L3 animals raised at 24C. Paper_evidence: WBPaper00001011
              Curator_confirmed: WBPerson712
          Temperature: 24 Paper_evidence: WBPaper00001011
              Curator_confirmed: WBPerson712
          Genotype: lin-14(n179) Paper_evidence: WBPaper00001011
              Curator_confirmed: WBPerson712
      WBPhenotype:0001581 Paper_evidence: WBPaper00001011
        Curator_confirmed: WBPerson712
        Remark: Animals have 29%(n=20) mutant seam cell nuclei, similar to XXX lin-14 animals (26% n=25) and less mutant than XX lin-14 animals (77% n=40). Paper_evidence: WBPaper00001011
            Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0006913 PATO:0000460 Paper_evidence: WBPaper00001011
                Curator_confirmed: WBPerson712
          Life_stage: WBls:0000035 PATO:0000460 Paper_evidence: WBPaper00001011
                Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: Animals were maintained at 24C for two to three generations to obtain enough animals to score. Nomarski optics were used to follow the fates of the midbody seam cell nuclei of L3 animals raised at 24C. Paper_evidence: WBPaper00001011
              Curator_confirmed: WBPerson712
          Temperature: 24 Paper_evidence: WBPaper00001011
              Curator_confirmed: WBPerson712
          Genotype: lin-14(n179) Paper_evidence: WBPaper00001011
              Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0000928 Paper_evidence: WBPaper00001011
        Curator_confirmed: WBPerson712
        Remark: Percent of lin-14 mutant seam cell nuclei in XO males is not different to that of males carrying lin-14 alone. Paper_evidence: WBPaper00001011
            Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000056 PATO:0000460 Paper_evidence: WBPaper00001011
                Curator_confirmed: WBPerson712
        Phenotype_assay: Temperature: 20 Paper_evidence: WBPaper00001011
              Curator_confirmed: WBPerson712
          Genotype: lin-14(n179)/0 Paper_evidence: WBPaper00001011
              Curator_confirmed: WBPerson712
      WBPhenotype:0001024 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: XO phenotype nearly wildtype male Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Maternal: With_maternal_effect: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0001175 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: unlike dpy-26- non-Him Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Maternal: With_maternal_effect: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
  Reference: WBPaper00001011
    WBPaper00016312
    WBPaper00016314
  Method: Allele