WormBase Tree Display for Variation: WBVar00241454

WBVar00241454 Evidence: Paper_evidence: WBPaper00018906
    Person_evidence: WBPerson453
  Name: Public_name: r1162
    Other_name (16)
    HGVSg: CHROMOSOME_V:g.6902386_6906045del
  Sequence_details: SMap: S_parent: Sequence: K11C4
    Flanking_sequences: agctctccgaaagcgtcgatgatcaaacct aaaaaaaaactataaaattcaagcaaatca
    Mapping_target: K11C4
    Type_of_mutation: Deletion
    SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00030699
      WBStrain00030700
      WBStrain00034950
      WBStrain00040880
      WBStrain00040882
      WBStrain00056731
    Laboratory: TR
      EN
    Status: Live
  Affects: Gene: WBGene00006801
    Transcript (16)
    Interactor: WBInteraction000519345
  Isolation: Mutagen: Tc1
  Genetics: Interpolated_map_position: V 0.459264
  Description: Phenotype: WBPhenotype:0000002 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: weak kinker, resembles e540 Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Ease_of_scoring: ES3_Easy_to_score: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000164 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: resembles e540 Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000561 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: head region but not body resistant to 1 mM levamisole, resembles e540 Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00004019 Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0005739 PATO:0000460 Person_evidence: WBPerson261
                Curator_confirmed: WBPerson712
      WBPhenotype:0000563 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: slight shrinker, resembles e540 Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000646 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: resembles e540 Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0001599 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: head region but not body resistant to ouabain, resembles e540 Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00001924 Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0005739 PATO:0000460 Person_evidence: WBPerson261
                Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0001645 Paper_evidence: WBPaper00040284
        Curator_confirmed: WBPerson2987
        Remark: Table S2 Paper_evidence: WBPaper00040284
            Curator_confirmed: WBPerson2987
  Reference: WBPaper00040284
    WBPaper00018906
    WBPaper00066013
  Remark: Variation information submitted by WBPerson453 on 2022-11-17_09:04:46 via the Allele submission form. Submitted data refers to the negative strand. Curator_confirmed: WBPerson51134
    Submitted comments: Mutation starts and ends in introns, the theoretical spliced mRNA has a frameshift and has a STOP codon after the protein sequenceFERQIKNVDAHGANELLLRHLSSKIRHRSRQDRLGAQ, 30 bp upstream: AAGgtacccacagacactgtagttttgtgtttgattcggttgcgttccacatctaatctattaaaattctcaaactctccaatagattgtgaataacccaacacccccttctaacccctaaaccaatttgcagAACGTTGACGCCCATGGCGCAAACGAACTGCTCTTACGTCACCTCTCATCGAAAATTCGACATCGATCCCGGCAAGATCGCCTCGGCGCACAGgtttcgagcccgcatattatctctatcaactgtcttttttcgcctgatttgcttgaattttatagttttttttt, 30 bp downstream: agGTTTGATCATCGACGCTTTCGGAGAGCTTCGTGATCAACAAGAATCTGCAACTGAGAAGCTCGAGTCATCATGTTTCATTTGCGACATCGGCAAAGAAACGTTTGATCGGATGCCTCGAGGCTTCGAAATTCACACCACCAAAGAGCACAACTTTGCCAATTACCTgtatgttaaatgcttttattcaactgttctaacttttcaaacttctagGTTCTTCTTACAACATCTGGTCAACAAAGACGAAACAGAGTACACTGGTCAAGAAACGTACGTACGTGAGAAGTACGATAATCG We obtained this strain from the CGC and sequenced the deletion. Person_evidence: WBPerson453
      Curator_confirmed: WBPerson51134
  Method: Deletion_allele