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WormBase Tree Display for Variation: WBVar00241100

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Name Class

WBVar00241100EvidencePaper_evidenceWBPaper00004647
NamePublic_nameq388
Other_nameT01H8.5d.2:c.2560G>A
CE41002:p.Glu894Lys
T01H8.5a.1:c.2863G>A
CE42821:p.Glu549Lys
CE41003:p.Glu854Lys
T01H8.5c.1:c.2680G>A
T01H8.5e.1:c.1645G>A
T01H8.5d.1:c.2560G>A
CE30390:p.Glu955Lys
HGVSgCHROMOSOME_I:g.8555229C>T
Sequence_detailsSMapS_parentSequenceT01H8
Flanking_sequencesactgaaccagatttccgttatccgtacagtaactcatgatatgggctgttttgacgaaaa
Mapping_targetT01H8
Type_of_mutationSubstitutionga
SeqStatusSequenced
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00007128
WBStrain00007130
WBStrain00049840
WBStrain00049841
LaboratoryJK
StatusLive
Linked_toWBVar02147594
WBVar02147596
WBVar02147597
WBVar02147599
WBVar02147601
WBVar02147606
AffectsGeneWBGene00001651
TranscriptT01H8.5e.1 (12)
T01H8.5a.1 (12)
T01H8.5d.1 (12)
T01H8.5c.1 (12)
T01H8.5d.2 (12)
InteractorWBInteraction000050597
WBInteraction000050598
WBInteraction000051953
WBInteraction000051954
WBInteraction000501216
WBInteraction000501217
WBInteraction000501218
WBInteraction000501219
WBInteraction000504554
WBInteraction000517362
IsolationMutagenEMS
GeneticsInterpolated_map_positionI2.94713
DescriptionPhenotypeWBPhenotype:0000688Paper_evidenceWBPaper00036046
Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Remarkzygotic sterile at 25C, fertile 15C, upshift gives Gon progenyPerson_evidenceWBPerson261
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitivePaper_evidenceWBPaper00036046
Curator_confirmedWBPerson712
25Person_evidenceWBPerson261
Curator_confirmedWBPerson712
WBPhenotype:0000691Paper_evidenceWBPaper00036046
Curator_confirmedWBPerson712
RemarkMg2+ supplementation can partially suppress the gonadogenesis defect of gon-2 mutants. Supplementation of the medium with 50 mM Mg2+ increased the frequency of non-vulvaless gon-2(q388) animals raised at 23.5 deg C. from 12% (n=763) to 64% (n=968).Paper_evidenceWBPaper00036046
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitivePaper_evidenceWBPaper00036046
Curator_confirmedWBPerson712
WBPhenotype:0000698Paper_evidenceWBPaper00036046
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitivePaper_evidenceWBPaper00036046
Curator_confirmedWBPerson712
WBPhenotype:0000836Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Remarkzygotic sterile at 25C, fertile 15C, upshift gives Gon progenyPerson_evidenceWBPerson261
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitive25Person_evidenceWBPerson261
Curator_confirmedWBPerson712
ReferenceWBPaper00018419
WBPaper00036046
WBPaper00010677
WBPaper00011070
WBPaper00019720
WBPaper00048884
WBPaper00065340
WBPaper00065841
MethodSubstitution_allele