WormBase Tree Display for Variation: WBVar00241038
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| WBVar00241038 | Evidence | Paper_evidence | WBPaper00001677 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Name | Public_name | q231 | |||||||
| Other_name | CE00237:p.Gly1057Glu | ||||||||
| F02A9.6.1:c.3170G>A | |||||||||
| HGVSg | CHROMOSOME_III:g.9098563G>A | ||||||||
| Sequence_details | SMap | S_parent | Sequence | F02A9 | |||||
| Flanking_sequences | tggagatggcagagcttcttctttcaaaag | agcaaaacttgattacgatggtgctgctag | |||||||
| Mapping_target | F02A9 | ||||||||
| Type_of_mutation | Substitution | g | a | Paper_evidence | WBPaper00001677 | ||||
| SeqStatus | Sequenced | ||||||||
| Variation_type | Allele | ||||||||
| Origin | Species | Caenorhabditis elegans | |||||||
| Strain | WBStrain00007142 | ||||||||
| WBStrain00022514 | |||||||||
| WBStrain00022527 | |||||||||
| WBStrain00022529 | |||||||||
| WBStrain00022531 | |||||||||
| WBStrain00022532 | |||||||||
| WBStrain00022542 | |||||||||
| WBStrain00027164 | |||||||||
| Laboratory | JK | ||||||||
| Status | Live | ||||||||
| Affects | Gene | WBGene00001609 | |||||||
| Transcript | F02A9.6.1 (12) | ||||||||
| Interactor | WBInteraction000502786 | ||||||||
| WBInteraction000517591 | |||||||||
| WBInteraction000518398 | |||||||||
| WBInteraction000555582 | |||||||||
| Isolation | Mutagen | EMS | |||||||
| Genetics | Interpolated_map_position | III | 0.16398 | ||||||
| Mapping_data | In_multi_point | 1734 | |||||||
| 2765 | |||||||||
| 2766 | |||||||||
| Description | Phenotype | WBPhenotype:0000080 | Paper_evidence | WBPaper00001007 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Penetrance | Complete | Paper_evidence | WBPaper00001007 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Range | 100 | 100 | Paper_evidence | WBPaper00001007 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001007 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Variation_effect | Hypomorph_reduction_of_function | Paper_evidence | WBPaper00001007 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0003681 | PATO:0000460 | Paper_evidence | WBPaper00001007 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Life_stage | WBls:0000024 | PATO:0000460 | Paper_evidence | WBPaper00001007 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Temperature_sensitive | Heat_sensitive | 25 | Paper_evidence | WBPaper00001007 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Maternal | |||||||||
| Phenotype_assay | Treatment | Embryos were shifted to the restrictive temperature at the 8-cell stage | Paper_evidence | WBPaper00001007 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000081 | Paper_evidence | WBPaper00001007 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Penetrance | Complete | Paper_evidence | WBPaper00001007 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Range | 100 | 100 | Paper_evidence | WBPaper00001007 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001007 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Variation_effect | Hypomorph_reduction_of_function | Paper_evidence | WBPaper00001007 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000024 | PATO:0000460 | Paper_evidence | WBPaper00001007 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Temperature_sensitive | Heat_sensitive | 25 | Paper_evidence | WBPaper00001007 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Maternal | |||||||||
| Phenotype_assay | Treatment | Embryos were shifted to the restrictive temperature at the 8-cell stage | Paper_evidence | WBPaper00001007 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000286 | Paper_evidence | WBPaper00001007 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | Although signs of pharyngeal differentiation is seen within the embryo, morphogenesis is defective, and a recognizable worm is not made. | Paper_evidence | WBPaper00001007 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Penetrance | Complete | Paper_evidence | WBPaper00001007 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Range | 100 | 100 | Paper_evidence | WBPaper00001007 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001007 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Variation_effect | Hypomorph_reduction_of_function | Paper_evidence | WBPaper00001007 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00001007 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Temperature_sensitive | Heat_sensitive | 25 | Paper_evidence | WBPaper00001007 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Maternal | Strictly_maternal | Paper_evidence | WBPaper00001007 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000412 | Paper_evidence | WBPaper00038400 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | Animals had a slightly impaired response to octanol. | Paper_evidence | WBPaper00038400 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Variation_effect | Hypomorph_reduction_of_function | Paper_evidence | WBPaper00038400 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Affected_by | Molecule | WBMol:00001966 | Paper_evidence | WBPaper00038400 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| Temperature_sensitive | Heat_sensitive | Paper_evidence | WBPaper00038400 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000684 | Paper_evidence | WBPaper00001007 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | Only 7-25 germ cells are produced in glp-1 mutants. All these germ cells differentiate into sperm | Paper_evidence | WBPaper00001007 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001007 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Variation_effect | Hypomorph_reduction_of_function | Paper_evidence | WBPaper00001007 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000056 | PATO:0000460 | Paper_evidence | WBPaper00001007 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBls:0000057 | PATO:0000460 | Paper_evidence | WBPaper00001007 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Temperature_sensitive | Heat_sensitive | 25 | Paper_evidence | WBPaper00001007 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000823 | Paper_evidence | WBPaper00001423 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | Mutants have a severely reduced germ line | Paper_evidence | WBPaper00001423 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Penetrance | Complete | Paper_evidence | WBPaper00001423 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Range | 100 | 100 | Paper_evidence | WBPaper00001423 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Variation_effect | Probable_null_via_phenotype | Paper_evidence | WBPaper00001423 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000041 | PATO:0000460 | Paper_evidence | WBPaper00001423 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Temperature_sensitive | Heat_sensitive | 25 | Paper_evidence | WBPaper00001423 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Phenotype_assay | Temperature | 25C | Paper_evidence | WBPaper00001423 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000867 | Paper_evidence | WBPaper00001007 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Penetrance | Complete | Paper_evidence | WBPaper00001007 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Range | 100 | 100 | Paper_evidence | WBPaper00001007 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001007 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Variation_effect | Hypomorph_reduction_of_function | Paper_evidence | WBPaper00001007 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00001007 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Temperature_sensitive | Heat_sensitive | 25 | Paper_evidence | WBPaper00001007 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Maternal | Strictly_maternal | Paper_evidence | WBPaper00001007 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Phenotype_not_observed | WBPhenotype:0000127 | Paper_evidence | WBPaper00031997 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | Animals did not recover significantly faster than wild type under the same conditions. | Paper_evidence | WBPaper00031997 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Variation_effect | Probable_null_via_phenotype | Paper_evidence | WBPaper00031997 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| EQ_annotations | Life_stage | WBls:0000032 | PATO:0000460 | Paper_evidence | WBPaper00031997 | ||||
| Curator_confirmed | WBPerson712 | ||||||||
| Phenotype_assay | Treatment | Dauers were induced by pheromone. | Paper_evidence | WBPaper00031997 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| Temperature | 25 | Paper_evidence | WBPaper00031997 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000395 | Paper_evidence | WBPaper00001007 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | Oocytes and sperm are functional | Paper_evidence | WBPaper00001007 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001007 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Variation_effect | Hypomorph_reduction_of_function | Paper_evidence | WBPaper00001007 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000041 | PATO:0000460 | Paper_evidence | WBPaper00001007 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000977 | Paper_evidence | WBPaper00001007 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001007 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Variation_effect | Hypomorph_reduction_of_function | Paper_evidence | WBPaper00001007 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000041 | PATO:0000460 | Paper_evidence | WBPaper00001007 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Reference | WBPaper00012645 | ||||||||
| WBPaper00038400 | |||||||||
| WBPaper00031997 | |||||||||
| WBPaper00014159 | |||||||||
| WBPaper00014700 | |||||||||
| WBPaper00001423 | |||||||||
| WBPaper00017752 | |||||||||
| WBPaper00012632 | |||||||||
| WBPaper00014629 | |||||||||
| WBPaper00001007 | |||||||||
| Method | Substitution_allele |
