WormBase Tree Display for Variation: WBVar00146665

WBVar00146665 Evidence: Paper_evidence: WBPaper00014587
  Name: Public_name: h752
  Sequence_details: SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00023863
    Laboratory: KR
    Status: Live
  Affects: Gene: WBGene00002704
  Genetics: Mapping_data: In_pos_neg_data: 6009
        6041
  Description: Phenotype: WBPhenotype:0000682 Paper_evidence: WBPaper00002829
        Curator_confirmed: WBPerson712
        Remark: Spermatogenesis failed to occur, but the germ cells did undergo oogenesis. Paper_evidence: WBPaper00002829
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00002829
          Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00002829
                Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: dpy-5 unc-13; sDp2 Paper_evidence: WBPaper00002829
              Curator_confirmed: WBPerson712
      WBPhenotype:0000684 Paper_evidence: WBPaper00002829
        Curator_confirmed: WBPerson712
        Remark: There appeared to be a reduced number of germ cells in the distal arms. Paper_evidence: WBPaper00002829
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00002829
          Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00002829
                Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: dpy-5 unc-13; sDp2 Paper_evidence: WBPaper00002829
              Curator_confirmed: WBPerson712
      WBPhenotype:0000688 Paper_evidence: WBPaper00003985
          WBPaper00002829
        Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: sterile adult mutants had a normal life-span of two to three weeks and grew to the expected size for Unc-13 adults (0.6+/-0.8 mm); oocytes didnot form embryos when fertilized by wild-type sperm, but the proximal gonad region near the vulva may not be properly formed. Paper_evidence: WBPaper00002829
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00002829
          Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00002829
                Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: dpy-5 unc-13; sDp2 Paper_evidence: WBPaper00002829
              Curator_confirmed: WBPerson712
      WBPhenotype:0000774 Paper_evidence: WBPaper00002829
        Curator_confirmed: WBPerson712
        Remark: These mutants arrested as adults and formed gonads, but had defects in germ cell proliferation, or in the formation of mature gametes. There appeared to be a reduced number of germ cells in the distal arms. Paper_evidence: WBPaper00002829
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00002829
          Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00002829
                Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: dpy-5 unc-13; sDp2 Paper_evidence: WBPaper00002829
              Curator_confirmed: WBPerson712
      WBPhenotype:0000823 Paper_evidence: WBPaper00002829
        Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00002829
          Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00002829
                Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: dpy-5 unc-13; sDp2 Paper_evidence: WBPaper00002829
              Curator_confirmed: WBPerson712
      WBPhenotype:0001970 Paper_evidence: WBPaper00002829
        Curator_confirmed: WBPerson712
        Remark: a reduced number of syncytial nuclei occur in the other half of the distal arms Paper_evidence: WBPaper00002829
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00002829
          Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00002829
                Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: dpy-5 unc-13; sDp2 Paper_evidence: WBPaper00002829
              Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0000670 Paper_evidence: WBPaper00002829
        Curator_confirmed: WBPerson712
        Remark: none of the sterile mutants were rescued by wild-type sperm, thereforenone of them had defects in spermatogenesis alone. Paper_evidence: WBPaper00002829
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00002829
          Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00002829
                Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: dpy-5 unc-13; sDp2 Paper_evidence: WBPaper00002829
              Curator_confirmed: WBPerson712
  Reference: WBPaper00002829
    WBPaper00014587
    WBPaper00003985
  Method: Allele