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WormBase Tree Display for Variation: WBVar00146512

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Name Class

WBVar00146512NamePublic_nameh271
Sequence_detailsSeqStatusPending_curation
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00023746
LaboratoryKR
StatusLive
AffectsGeneWBGene00002615
GeneticsMapping_dataIn_pos_neg_data (12)
DescriptionPhenotypeWBPhenotype:0000447Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
Remarkhomozygotes for let-395(h271) arrested as young adults.Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
RecessivePaper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000041PATO:0000460Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
Phenotype_assayGenotypedpy-5 unc-13; sDp2Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
WBPhenotype:0000688Paper_evidenceWBPaper00003985
WBPaper00002829
Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Remarksterile adult mutants had a normal life-span of two to three weeks and grew to the expected size for Unc-13 adults (0.6+/-0.8 mm)Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
RecessivePaper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000041PATO:0000460Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
Phenotype_assayGenotypedpy-5 unc-13; sDp2Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
WBPhenotype:0000691Paper_evidenceWBPaper00002829
Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Remarkundeveloped gonad.Person_evidenceWBPerson261
Curator_confirmedWBPerson712
mutants failed to develop a normal gonad; DAPI staining revealed a group of nuclei clustered at the vulva but no structure that could be recognized as a gonad was observedPaper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
RecessivePaper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000041PATO:0000460Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
Phenotype_assayGenotypedpy-5 unc-13; sDp2Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
Phenotype_not_observedWBPhenotype:0000670Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
Remarknone of the sterile mutants were rescued by wild-type sperm, thereforenone of them had defects in spermatogenesis alone.Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
RecessivePaper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000041PATO:0000460Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
Phenotype_assayGenotypedpy-5 unc-13; sDp2Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
ReferenceWBPaper00002829
WBPaper00003985
MethodAllele