WormBase Tree Display for Variation: WBVar00145323
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WBVar00145323 | Evidence | Paper_evidence | WBPaper00002037 | |||||
---|---|---|---|---|---|---|---|---|
Name | Public_name | fc30 | ||||||
Sequence_details | SeqStatus | Pending_curation | ||||||
Variation_type | Allele | |||||||
Origin | Species | Caenorhabditis elegans | ||||||
Laboratory | CW | |||||||
Status | Live | |||||||
Affects | Interactor | WBInteraction000052204 | ||||||
Description | Phenotype | WBPhenotype:0000646 | Paper_evidence | WBPaper00002037 | ||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Animals are mildly slow in the absence of anesthetic. | Paper_evidence | WBPaper00002037 | |||||
Curator_confirmed | WBPerson712 | |||||||
Recessive | Paper_evidence | WBPaper00002037 | ||||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0001606 | Paper_evidence | WBPaper00002358 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Animals have a lower EC50 (650 40mM) compared to N2 (1050 25 mM). | Paper_evidence | WBPaper00002358 | |||||
Curator_confirmed | WBPerson712 | |||||||
Phenotype_assay | Treatment | 50 animals were scored for mobility for 10 sec. at each concentration of ethanol after 5 min exposure. EC50's (concentration at which 50% of the animals were immobile for >10 sec) were determined from a dose response curve over a minimum of 12 concentrations (mM). Immobility was used an as endpoint. Upon removal from ethanol, immobility was reversible within 10-15 min. Treatment and scoring of anesthetic responses are described in Sedensky and Meneely, 1987; Morgan et al. , 1990; Morgan and Sedensky, 1994. | Paper_evidence | WBPaper00002358 | ||||
Curator_confirmed | WBPerson712 | |||||||
Temperature | 22-24C | Paper_evidence | WBPaper00002358 | |||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0001608 | Paper_evidence | WBPaper00002037 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Animals have a lower EC50 (4.2 0.2 vol%) compared to N2 (6.1 0.1 vol%). | Paper_evidence | WBPaper00002037 | |||||
Curator_confirmed | WBPerson712 | |||||||
Recessive | Paper_evidence | WBPaper00002037 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Phenotype_assay | Treatment | 50 animals were scored for mobility for 10 sec at each concentration of anesthetic. Immobility was used as the end point, which in all cases was reversible 10-15 min after removal from the anesthetic. Animals were tested over a minimum of 12 concentrations. EC50 = percent volume at which 50% animals were immobile for 10 sec. | Paper_evidence | WBPaper00002037 | ||||
Curator_confirmed | WBPerson712 | |||||||
Temperature | 22-24C | Paper_evidence | WBPaper00002037 | |||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0001609 | Paper_evidence | WBPaper00002037 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Animals have a lower EC50 (4.0 0.2 vol%) compared to N2 (7.1 0.1 vol%). | Paper_evidence | WBPaper00002037 | |||||
Curator_confirmed | WBPerson712 | |||||||
Recessive | Paper_evidence | WBPaper00002037 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Phenotype_assay | Treatment | 50 animals were scored for mobility for 10 sec at each concentration of anesthetic. Immobility was used as the end point, which in all cases was reversible 10-15 min after removal from the anesthetic. Animals were tested over a minimum of 12 concentrations. EC50 = percent volume at which 50% animals were immobile for 10 sec. | Paper_evidence | WBPaper00002037 | ||||
Curator_confirmed | WBPerson712 | |||||||
Temperature | 22-24C | Paper_evidence | WBPaper00002037 | |||||
Curator_confirmed | WBPerson712 | |||||||
Phenotype_not_observed | WBPhenotype:0000231 | Paper_evidence | WBPaper00002037 | |||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Animals are normal in length. | Paper_evidence | WBPaper00002037 | |||||
Curator_confirmed | WBPerson712 | |||||||
Recessive | Paper_evidence | WBPaper00002037 | ||||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0001610 | Paper_evidence | WBPaper00002037 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Animals have a similar EC50 (5.8 0.3 vol%) compared to N2 (6.5 0.2 vol%). | Paper_evidence | WBPaper00002037 | |||||
Curator_confirmed | WBPerson712 | |||||||
Recessive | Paper_evidence | WBPaper00002037 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Phenotype_assay | Treatment | 50 animals were scored for mobility for 10 sec at each concentration of anesthetic. Immobility was used as the end point, which in all cases was reversible 10-15 min after removal from the anesthetic. Animals were tested over a minimum of 12 concentrations. EC50 = percent volume at which 50% animals were immobile for 10 sec. | Paper_evidence | WBPaper00002037 | ||||
Curator_confirmed | WBPerson712 | |||||||
Temperature | 22-24C | Paper_evidence | WBPaper00002037 | |||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0001611 | Paper_evidence | WBPaper00002037 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Animals have a similar EC50 (2.7 0.1 vol%) compared to N2 (3.2 0.1 vol%). | Paper_evidence | WBPaper00002037 | |||||
Curator_confirmed | WBPerson712 | |||||||
Phenotype_assay | Treatment | 50 animals were scored for mobility for 10 sec at each concentration of anesthetic. Immobility was used as the end point, which in all cases was reversible 10-15 min after removal from the anesthetic. Animals were tested over a minimum of 12 concentrations. EC50 = percent volume at which 50% animals were immobile for 10 sec. | Paper_evidence | WBPaper00002037 | ||||
Curator_confirmed | WBPerson712 | |||||||
Temperature | 22-24C | Paper_evidence | WBPaper00002037 | |||||
Curator_confirmed | WBPerson712 | |||||||
Reference | WBPaper00002358 | |||||||
WBPaper00002037 | ||||||||
Method | Allele |