Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Variation: WBVar00145319

expand all nodes | collapse all nodes | view schema

Name Class

WBVar00145319EvidencePaper_evidenceWBPaper00002037
NamePublic_namefc23
Sequence_detailsSeqStatusPending_curation
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
LaboratoryCW
StatusLive
AffectsInteractorWBInteraction000052203
DescriptionPhenotypeWBPhenotype:0000324Paper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
WBPhenotype:0000642Paper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
RemarkAnimals exhibit vigorous motion. in the absence of anesthetic.Paper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
WBPhenotype:0001606Paper_evidenceWBPaper00002358
Curator_confirmedWBPerson712
RemarkAnimals have a lower EC50 (710 35mM) compared to N2 (1050 25 mM).Paper_evidenceWBPaper00002358
Curator_confirmedWBPerson712
Phenotype_assayTreatment50 animals were scored for mobility for 10 sec. at each concentration of ethanol after 5 min exposure. EC50's (concentration at which 50% of the animals were immobile for >10 sec) were determined from a dose response curve over a minimum of 12 concentrations (mM). Immobility was used an as endpoint. Upon removal from ethanol, immobility was reversible within 10-15 min. Treatment and scoring of anesthetic responses are described in Sedensky and Meneely, 1987; Morgan et al. , 1990; Morgan and Sedensky, 1994.Paper_evidenceWBPaper00002358
Curator_confirmedWBPerson712
Temperature22-24CPaper_evidenceWBPaper00002358
Curator_confirmedWBPerson712
WBPhenotype:0001608Paper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
RemarkAnimals have a lower EC50 (4.5 0.2 vol%) compared to N2 (6.1 0.1 vol%).Paper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
RecessivePaper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
Phenotype_assayTreatment50 animals were scored for mobility for 10 sec at each concentration of anesthetic. Immobility was used as the end point, which in all cases was reversible 10-15 min after removal from the anesthetic. Animals were tested over a minimum of 12 concentrations. EC50 = percent volume at which 50% animals were immobile for 10 sec.Paper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
Temperature22-24CPaper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
WBPhenotype:0001609Paper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
RemarkAnimals have a lower EC50 (4.2 0.2 vol%) compared to N2 (7.1 0.1 vol%).Paper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
RecessivePaper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
Phenotype_assayTreatment50 animals were scored for mobility for 10 sec at each concentration of anesthetic. Immobility was used as the end point, which in all cases was reversible 10-15 min after removal from the anesthetic. Animals were tested over a minimum of 12 concentrations. EC50 = percent volume at which 50% animals were immobile for 10 sec.Paper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
Temperature22-24CPaper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
Phenotype_not_observedWBPhenotype:0001610Paper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
RemarkAnimals have a similar EC50 (6.0 0.3 vol%) compared to N2 (6.5 0.2 vol%).Paper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
RecessivePaper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
Phenotype_assayTreatment50 animals were scored for mobility for 10 sec at each concentration of anesthetic. Immobility was used as the end point, which in all cases was reversible 10-15 min after removal from the anesthetic. Animals were tested over a minimum of 12 concentrations. EC50 = percent volume at which 50% animals were immobile for 10 sec.Paper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
Temperature22-24CPaper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
WBPhenotype:0001611Paper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
RemarkAnimals have a similar EC50 (2.9 0.1 vol%) compared to N2 (3.2 0.1 vol%).Paper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
RecessivePaper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
Phenotype_assayTreatment50 animals were scored for mobility for 10 sec at each concentration of anesthetic. Immobility was used as the end point, which in all cases was reversible 10-15 min after removal from the anesthetic. Animals were tested over a minimum of 12 concentrations. EC50 = percent volume at which 50% animals were immobile for 10 sec.Paper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
Temperature22-24CPaper_evidenceWBPaper00002037
Curator_confirmedWBPerson712
ReferenceWBPaper00002358
WBPaper00002037
MethodAllele