WormBase Tree Display for Variation: WBVar00144939
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| WBVar00144939 | Evidence | Paper_evidence | WBPaper00026735 | |||||
|---|---|---|---|---|---|---|---|---|
| Name | Public_name | e2709 | ||||||
| Sequence_details | SeqStatus | Pending_curation | ||||||
| Variation_type | Allele | |||||||
| Origin | Species | Caenorhabditis elegans | ||||||
| Strain | WBStrain00004669 | |||||||
| Laboratory | CB | |||||||
| Status | Live | |||||||
| Affects | Gene | WBGene00044628 | ||||||
| Isolation | Mutagen | EMS | ||||||
| Description | Phenotype | WBPhenotype:0001014 | Person_evidence | WBPerson261 | ||||
| Curator_confirmed | WBPerson48 | |||||||
| Remark | Resistant to infection by M. nematophilum. | Person_evidence | WBPerson261 | |||||
| Curator_confirmed | WBPerson48 | |||||||
| Penetrance | Complete | Person_evidence | WBPerson261 | |||||
| Curator_confirmed | WBPerson48 | |||||||
| Recessive | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson48 | |||||||
| Variation_effect | Loss_of_function_undetermined_extent | Person_evidence | WBPerson261 | |||||
| Curator_confirmed | WBPerson48 | |||||||
| WBPhenotype:0001411 | Paper_evidence | WBPaper00026735 | ||||||
| Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson48 | |||||||
| Remark | Lectin staining abnormal. | Person_evidence | WBPerson261 | |||||
| Curator_confirmed | WBPerson48 | |||||||
| Based on lectin binding properties to the cuticle | Paper_evidence | WBPaper00026735 | ||||||
| Curator_confirmed | WBPerson48 | |||||||
| Phenotype_assay | Treatment | Tested the following fluorescein or rhodamine-conjugated lectins: WGA, SBA, TPA, PEA,, CON, LEA. | Paper_evidence | WBPaper00026735 | ||||
| Curator_confirmed | WBPerson48 | |||||||
| WBPhenotype:0001413 | Paper_evidence | WBPaper00026735 | ||||||
| Curator_confirmed | WBPerson48 | |||||||
| Remark | Slight tail swelling when grown on pure M. nematophilum. | Paper_evidence | WBPaper00026735 | |||||
| Curator_confirmed | WBPerson48 | |||||||
| Penetrance | Incomplete | variable | Paper_evidence | WBPaper00026735 | ||||
| Curator_confirmed | WBPerson48 | |||||||
| WBPhenotype:0001416 | Paper_evidence | WBPaper00026735 | ||||||
| Curator_confirmed | WBPerson48 | |||||||
| Remark | Based on vital dye staining for bacteria to reveal M. nematophilum; reduced rectal staining, indicating reduced adherence in the usual region. | Paper_evidence | WBPaper00026735 | |||||
| Curator_confirmed | WBPerson48 | |||||||
| Phenotype_not_observed | WBPhenotype:0001212 | Paper_evidence | WBPaper00026735 | |||||
| Curator_confirmed | WBPerson48 | |||||||
| Remark | Based on a comparison of bleach sensitivity with wild type worms. | Paper_evidence | WBPaper00026735 | |||||
| Curator_confirmed | WBPerson48 | |||||||
| WBPhenotype:0001420 | Paper_evidence | WBPaper00029153 | ||||||
| WBPaper00031925 | ||||||||
| Curator_confirmed | WBPerson712 | |||||||
| Remark | No difference was observed between mutant and wild-type in terms of the amount of biofilm accumulated on the nose of the worm. | Paper_evidence | WBPaper00029153 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| A similar percentage of animals accumulate biofilm produced by Xenorhabdus nematophila on their heads to that of Wild type. | Paper_evidence | WBPaper00031925 | ||||||
| Curator_confirmed | WBPerson712 | |||||||
| Phenotype_assay | Treatment | Biofilm formation on adult worms was assessed for worms incubated 24-48 hours on the bacterial lawn. Alternatively, gravid adults were allowed to lay eggs on bacterial lawns for several hours, then removed and larvae were assessed for biofilm attachment the next day. | Paper_evidence | WBPaper00031925 | ||||
| Curator_confirmed | WBPerson712 | |||||||
| Reference | WBPaper00026735 | |||||||
| WBPaper00031925 | ||||||||
| WBPaper00029153 | ||||||||
| Method | Allele |
