WormBase Tree Display for Variation: WBVar00144918

WBVar00144918 Evidence: Paper_evidence: WBPaper00026735
  Name: Public_name: e2687
  Sequence_details: SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00004657
    Laboratory: CB
    Status: Live
  Affects: Gene: WBGene00044618
  Isolation: Mutagen: EMS
  Description: Phenotype: WBPhenotype:0001012 Paper_evidence: WBPaper00037686
        Curator_confirmed: WBPerson712
        Remark: Animals are able to even less efficiently across bands of CBX120 (Bacillus pumilus) bacteria growth (hurdles) than wild type animals; almost all animals remain stuck at the first of three hurdles, while wild type worms can move through these bands, even through it is with great difficulty. Paper_evidence: WBPaper00037686
            Curator_confirmed: WBPerson712
      WBPhenotype:0001014 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson48
        Remark: Resistant to infection by M. nematophilum -- fails to swell. Person_evidence: WBPerson261
            Curator_confirmed: WBPerson48
        Penetrance: Complete: Person_evidence: WBPerson261
              Curator_confirmed: WBPerson48
        Recessive: Person_evidence: WBPerson261
          Curator_confirmed: WBPerson48
        Variation_effect: Loss_of_function_undetermined_extent: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson48
      WBPhenotype:0001212 Paper_evidence: WBPaper00026735
        Curator_confirmed: WBPerson48
        Remark: Mildly more fragile than wild type, based on a comparison of bleach sensitivity. Paper_evidence: WBPaper00026735
            Curator_confirmed: WBPerson48
      WBPhenotype:0001413 Paper_evidence: WBPaper00026735
          WBPaper00037686
        Curator_confirmed: WBPerson48
          WBPerson712
        Remark: Likely null or severe hypomorph. Paper_evidence: WBPaper00037686
            Curator_confirmed: WBPerson712
        Variation_effect: Hypomorph_reduction_of_function: Paper_evidence: WBPaper00037686
            Curator_confirmed: WBPerson712
      WBPhenotype:0001416 Paper_evidence: WBPaper00026735
        Curator_confirmed: WBPerson48
        Remark: Based on vital dye staining for bacteria to reveal M. nematophilum; little rectal staining, indicating little adherence in the usual region. Paper_evidence: WBPaper00026735
            Curator_confirmed: WBPerson48
      WBPhenotype:0001420 Paper_evidence: WBPaper00029153
          WBPaper00031925
        Curator_confirmed: WBPerson712
        Remark: Animals are completely resistant to attachment of biofilm produced by Xenorhabdus nematophila. Paper_evidence: WBPaper00031925
            Curator_confirmed: WBPerson712
        Penetrance: Complete: Paper_evidence: WBPaper00031925
              Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: Biofilm formation on adult worms was assessed for worms incubated 24-48 hours on the bacterial lawn. Alternatively, gravid adults were allowed to lay eggs on bacterial lawns for several hours, then removed and larvae were assessed for biofilm attachment the next day. Paper_evidence: WBPaper00031925
              Curator_confirmed: WBPerson712
      WBPhenotype:0002159 Paper_evidence: WBPaper00045395
        Curator_confirmed: WBPerson499
      WBPhenotype:0002354 Paper_evidence: WBPaper00045395
        Curator_confirmed: WBPerson499
      WBPhenotype:0002462 Paper_evidence: WBPaper00045395
        Curator_confirmed: WBPerson499
        Remark: increased fungal spore adhesion Paper_evidence: WBPaper00045395
            Curator_confirmed: WBPerson499
      WBPhenotype:0004006 Paper_evidence: WBPaper00037686
        Curator_confirmed: WBPerson712
        Remark: Hermaphrodites experienced significantly reduced contact times by males during mating. Paper_evidence: WBPaper00037686
            Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0000031 Paper_evidence: WBPaper00037686
        Curator_confirmed: WBPerson712
        Remark: Animals did not exhibit any conspicuous difference from wild type. Paper_evidence: WBPaper00037686
            Curator_confirmed: WBPerson712
      WBPhenotype:0000145 Paper_evidence: WBPaper00037686
        Curator_confirmed: WBPerson712
        Remark: Animals did not exhibit any conspicuous differences from wild type. Paper_evidence: WBPaper00037686
            Curator_confirmed: WBPerson712
      WBPhenotype:0001209 Paper_evidence: WBPaper00037686
        Curator_confirmed: WBPerson712
        Remark: Animals move almost normally under normal laboratory conditions. Paper_evidence: WBPaper00037686
            Curator_confirmed: WBPerson712
      WBPhenotype:0001411 Paper_evidence: WBPaper00026735
        Curator_confirmed: WBPerson48
        Remark: Based on lectin binding properties to the cuticle, LEA not tested Paper_evidence: WBPaper00026735
            Curator_confirmed: WBPerson48
        Phenotype_assay: Treatment: Tested the following fluorescein or rhodamine-conjugated lectins: WGA, SBA, TPA, PEA,, CON, LEA. Paper_evidence: WBPaper00026735
              Curator_confirmed: WBPerson48
  Reference: WBPaper00026735
    WBPaper00031925
    WBPaper00029153
    WBPaper00037686
    WBPaper00045395
  Method: Allele