WormBase Tree Display for Variation: WBVar00144909
expand all nodes | collapse all nodes | view schema
| WBVar00144909 | Evidence | Paper_evidence | WBPaper00026735 | |||||
|---|---|---|---|---|---|---|---|---|
| Name | Public_name | e2678 | ||||||
| Sequence_details | SeqStatus | Pending_curation | ||||||
| Variation_type | Allele | |||||||
| Origin | Species | Caenorhabditis elegans | ||||||
| Strain | WBStrain00004656 | |||||||
| Laboratory | CB | |||||||
| Status | Live | |||||||
| Affects | Gene | WBGene00044617 | ||||||
| Isolation | Mutagen | EMS | ||||||
| Genetics | Mapping_data | In_multi_point | 5455 | |||||
| Description | Phenotype | WBPhenotype:0001014 | Person_evidence | WBPerson261 | ||||
| Curator_confirmed | WBPerson48 | |||||||
| Remark | Resistant to infection by M. nematophilum -- fails to swell. | Person_evidence | WBPerson261 | |||||
| Curator_confirmed | WBPerson48 | |||||||
| Penetrance | Complete | Person_evidence | WBPerson261 | |||||
| Curator_confirmed | WBPerson48 | |||||||
| Recessive | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson48 | |||||||
| Variation_effect | Loss_of_function_undetermined_extent | Person_evidence | WBPerson261 | |||||
| Curator_confirmed | WBPerson48 | |||||||
| WBPhenotype:0001413 | Paper_evidence | WBPaper00026735 | ||||||
| Curator_confirmed | WBPerson48 | |||||||
| WBPhenotype:0001416 | Paper_evidence | WBPaper00026735 | ||||||
| Curator_confirmed | WBPerson48 | |||||||
| Remark | Based on vital dye staining for bacteria to reveal M. nematophilum; no rectal staining, indicating no adherence in the usual region. | Paper_evidence | WBPaper00026735 | |||||
| Curator_confirmed | WBPerson48 | |||||||
| WBPhenotype:0002378 | Paper_evidence | WBPaper00054670 | ||||||
| Curator_confirmed | WBPerson2706 | |||||||
| Remark | animals defective in their ability to avoid OP50 lawns contaminated with Microbacterium nematophilum | Paper_evidence | WBPaper00054670 | |||||
| Curator_confirmed | WBPerson2706 | |||||||
| Phenotype_not_observed | WBPhenotype:0001212 | Paper_evidence | WBPaper00026735 | |||||
| Curator_confirmed | WBPerson48 | |||||||
| Remark | Based on a comparison of bleach sensitivity with wild type worms. | Paper_evidence | WBPaper00026735 | |||||
| Curator_confirmed | WBPerson48 | |||||||
| WBPhenotype:0001411 | Paper_evidence | WBPaper00026735 | ||||||
| Curator_confirmed | WBPerson48 | |||||||
| Remark | Based on lectin binding properties to the cuticle | Paper_evidence | WBPaper00026735 | |||||
| Curator_confirmed | WBPerson48 | |||||||
| Phenotype_assay | Treatment | Tested the following fluorescein or rhodamine-conjugated lectins: WGA, SBA, TPA, PEA,, CON, LEA. | Paper_evidence | WBPaper00026735 | ||||
| Curator_confirmed | WBPerson48 | |||||||
| WBPhenotype:0001420 | Paper_evidence | WBPaper00029153 | ||||||
| WBPaper00031925 | ||||||||
| Curator_confirmed | WBPerson712 | |||||||
| Remark | No difference was observed between mutant and wild-type in terms of the amount of biofilm accumulated on the nose of the worm. | Paper_evidence | WBPaper00029153 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| A similar percentage of animals accumulate biofilm produced by Xenorhabdus nematophila on their heads to that of Wild type. | Paper_evidence | WBPaper00031925 | ||||||
| Curator_confirmed | WBPerson712 | |||||||
| Phenotype_assay | Treatment | Biofilm formation on adult worms was assessed for worms incubated 24-48 hours on the bacterial lawn. Alternatively, gravid adults were allowed to lay eggs on bacterial lawns for several hours, then removed and larvae were assessed for biofilm attachment the next day. | Paper_evidence | WBPaper00031925 | ||||
| Curator_confirmed | WBPerson712 | |||||||
| Reference | WBPaper00026735 | |||||||
| WBPaper00031925 | ||||||||
| WBPaper00029153 | ||||||||
| WBPaper00054670 | ||||||||
| Method | Allele |
