WormBase Tree Display for Variation: WBVar00144591

WBVar00144591 Evidence: Paper_evidence: WBPaper00001677
  Name: Public_name: e2142
    Other_name: CE00237:p.Gly33Arg
      F02A9.6.1:c.97G>A
    HGVSg: CHROMOSOME_III:g.9092409G>A
  Sequence_details: SMap: S_parent: Sequence: F02A9
    Flanking_sequences: tgcggaagggaaggtgcttgctccgtcaat gaaaatgctataatggaaaactgattgaga
    Mapping_target: F02A9
    Type_of_mutation: Substitution: g a Paper_evidence: WBPaper00001677
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00022512
      WBStrain00049799
      WBStrain00049800
      WBStrain00049804
      WBStrain00049805
    Laboratory: CB
    Status: Live
  Affects: Gene: WBGene00001609
    Transcript: F02A9.6.1 (12)
    Interactor: WBInteraction000520251
      WBInteraction000520252
      WBInteraction000558928
  Isolation: Mutagen: EMS
  Genetics: Interpolated_map_position: III 0.161018
  Description: Phenotype: WBPhenotype:0000050 Paper_evidence: WBPaper00001008
        Curator_confirmed: WBPerson2021
        Remark: The end of temperature sensitive period for the Emb phenotype is near the 28 cell stage Paper_evidence: WBPaper00001008
            Curator_confirmed: WBPerson2021
        Penetrance: Complete: At 15C, 39 percent of mutants are Emb. At 25C, 100 percent of mutants are Emb Paper_evidence: WBPaper00001008
              Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001008
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000003 PATO:0000460 Paper_evidence: WBPaper00001008
                Curator_confirmed: WBPerson2021
        Temperature_sensitive: Heat_sensitive: 25 Paper_evidence: WBPaper00001008
              Curator_confirmed: WBPerson2021
        Maternal: Strictly_maternal: Paper_evidence: WBPaper00001008
            Curator_confirmed: WBPerson2021
        Phenotype_assay: Temperature: 15C, 25C Paper_evidence: WBPaper00001008
              Curator_confirmed: WBPerson2021
      WBPhenotype:0000189 Paper_evidence: WBPaper00001008
        Curator_confirmed: WBPerson2021
        Remark: Hypodermal cells are variably mispositioned in glp-1 mutants. Hypodermis fails to correctly subdivide into distinct dorsal, lateral, and ventral rows of cells at 25C Paper_evidence: WBPaper00001008
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001008
          Curator_confirmed: WBPerson2021
        EQ_annotations: Anatomy_term: WBbt:0005733 PATO:0000460 Paper_evidence: WBPaper00001008
                Curator_confirmed: WBPerson2021
          Life_stage: WBls:0000003 PATO:0000460 Paper_evidence: WBPaper00001008
                Curator_confirmed: WBPerson2021
        Temperature_sensitive: Heat_sensitive: 25 Paper_evidence: WBPaper00001008
              Curator_confirmed: WBPerson2021
        Maternal: Strictly_maternal: Paper_evidence: WBPaper00001008
            Curator_confirmed: WBPerson2021
        Phenotype_assay: Temperature: 25C Paper_evidence: WBPaper00001008
              Curator_confirmed: WBPerson2021
      WBPhenotype:0000242 Paper_evidence: WBPaper00001008
        Curator_confirmed: WBPerson2021
        Remark: Many glp-1 embryos do not elongate at 25C Paper_evidence: WBPaper00001008
            Curator_confirmed: WBPerson2021
        Penetrance: High: Paper_evidence: WBPaper00001008
              Curator_confirmed: WBPerson2021
          Range: 90 90 Paper_evidence: WBPaper00001008
                Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001008
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000003 PATO:0000460 Paper_evidence: WBPaper00001008
                Curator_confirmed: WBPerson2021
        Temperature_sensitive: Heat_sensitive: 25 Paper_evidence: WBPaper00001008
              Curator_confirmed: WBPerson2021
        Maternal: Strictly_maternal: Paper_evidence: WBPaper00001008
            Curator_confirmed: WBPerson2021
        Phenotype_assay: Temperature: 25C Paper_evidence: WBPaper00001008
              Curator_confirmed: WBPerson2021
    Phenotype_not_observed: WBPhenotype:0000688 Paper_evidence: WBPaper00001008
        Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001008
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00001008
                Curator_confirmed: WBPerson2021
        Phenotype_assay: Temperature: 15C, 25C Paper_evidence: WBPaper00001008
              Curator_confirmed: WBPerson2021
  Reference (15)
  Remark: Variation stub/paper connection generated from the May 2021 NN VFP dataset.
    Created by WBPerson51134 from the NN_VFP_triage_pipeline
  Method: Substitution_allele