WormBase Tree Display for Variation: WBVar00144552
expand all nodes | collapse all nodes | view schema
| WBVar00144552 | Name | Public_name | e2088 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Sequence_details | SeqStatus | Pending_curation | |||||||
| Variation_type | Allele | ||||||||
| Origin | Species | Caenorhabditis elegans | |||||||
| Strain | WBStrain00004806 | ||||||||
| WBStrain00004819 | |||||||||
| Laboratory | CB | ||||||||
| Status | Live | ||||||||
| Affects | Gene | WBGene00003102 | |||||||
| Interactor | WBInteraction000519197 | ||||||||
| WBInteraction000520380 | |||||||||
| WBInteraction000524197 | |||||||||
| WBInteraction000524205 | |||||||||
| WBInteraction000524206 | |||||||||
| WBInteraction000538767 | |||||||||
| WBInteraction000538768 | |||||||||
| WBInteraction000538769 | |||||||||
| Description | Phenotype | WBPhenotype:0000239 | Paper_evidence | WBPaper00004710 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | In mab-5(lf) single mutants, P9.p and P10.p still fused with hyp7, as in wild type. P11.p, however, is sometimes transformed into a copy of its posterior neighbor, P12.p. | Paper_evidence | WBPaper00004710 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Variation_effect | Probable_null_via_phenotype | Paper_evidence | WBPaper00004710 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000469 | Paper_evidence | WBPaper00002582 | |||||||
| WBPaper00003383 | |||||||||
| WBPaper00001492 | |||||||||
| WBPaper00004437 | |||||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPerson2987 | |||||||||
| Remark | QL initially migrated posteriorly; however, her descendants migrated towards the anterior. The final position of QL.pa daughters were displaced anteriorly compared to controls. | Paper_evidence | WBPaper00002582 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| mab-5(e2088) results in 0% of descendants of the QL neuroblast in the posterior of the animal, where the cell migrates in wild type (Table 1). | Paper_evidence | WBPaper00003383 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| QL descendants aberrantly migrate to the anterior of the animal, similar to QR descendants (Figure 1); "Changes in mab-5 activity do, however, strongly affect the migratory behaviours of the Q daughters, Q.a and Q.p, and their descendants. In a mab-5(e2088lf) background, these cells migrate anteriorly on both sides (Fig. lc), as seen on the wildtype right side. This shows that mab-5(+) activity is necessary to prevent the QL descendants from migrating anteriorly." | Paper_evidence | WBPaper00001492 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| QL.pax cells aberrantly migrate to the anterior of the animal (Figure 7) | Paper_evidence | WBPaper00004437 | |||||||
| Variation_effect | Loss_of_function_undetermined_extent | Paper_evidence | WBPaper00001492 | ||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| Probable_null_via_phenotype | Paper_evidence | WBPaper00002582 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0004056 | PATO:0000460 | Paper_evidence | WBPaper00003383 | ||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBbt:0007274 | PATO:0000460 | Paper_evidence | WBPaper00001492 | ||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBbt:0004096 | PATO:0000460 | Paper_evidence | WBPaper00001492 | ||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBbt:0007276 | PATO:0000460 | Paper_evidence | WBPaper00001492 | ||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBbt:0007277 | PATO:0000460 | Paper_evidence | WBPaper00001492 | ||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBbt:0004086 | PATO:0000460 | Paper_evidence | WBPaper00001492 | ||||||
| WBPaper00004437 | |||||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBbt:0004993 | PATO:0000460 | Paper_evidence | WBPaper00001492 | ||||||
| WBPaper00004437 | |||||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| Life_stage | WBls:0000024 | PATO:0000460 | Paper_evidence | WBPaper00003383 | |||||
| Curator_confirmed | WBPerson2987 | ||||||||
| GO_term | GO:0016477 | PATO:0000460 | Paper_evidence | WBPaper00001492 | |||||
| WBPaper00004437 | |||||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| Phenotype_assay | Genotype | him-5(e1490) | Paper_evidence | WBPaper00001492 | |||||
| Curator_confirmed | WBPerson2987 | ||||||||
| Reference (12) | |||||||||
| Method | Allele |
