WormBase Tree Display for Variation: WBVar00144489

WBVar00144489 Evidence: Paper_evidence: WBPaper00001824
  Name: Public_name: e2020
    Other_name: C15F1.3a.1:c.*59_*166del
    HGVSg: CHROMOSOME_II:g.6955453_6955560del
  Sequence_details: SMap: S_parent: Sequence: F22D3
    Flanking_sequences: TTCCAAAATTTCATTTCTTACTCATTTTCG ACTTGTAATCTTTACGAATTTTGTTTTCTT
    Mapping_target: F22D3
    Type_of_mutation: Deletion
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00004506
      WBStrain00004628
    Laboratory: CB
    Status: Live
  Affects: Gene: WBGene00006605
    Transcript: C15F1.3a.1 VEP_consequence: 3_prime_UTR_variant
        VEP_impact: MODIFIER
        HGVSc: C15F1.3a.1:c.*59_*166del
        cDNA_position: 4487-4594
        Exon_number: 24/24
    Interactor: WBInteraction000576797
  Genetics: Interpolated_map_position: II 0.149994
  Description: Phenotype: WBPhenotype:0000424 Paper_evidence: WBPaper00028730
        Curator_confirmed: WBPerson712
        Remark: the intestinal nuclei of rpn-10; ufd-2 (RNAi)-treated worms as well as gain-of-function mutant tra-2 (e2020) were stained more strongly than those of wild-type worms (vector RNAi control) Paper_evidence: WBPaper00028730
            Curator_confirmed: WBPerson712
        Variation_effect: Gain_of_function_undetermined_type: Paper_evidence: WBPaper00028730
            Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0005792 PATO:0000460 Paper_evidence: WBPaper00028730
                Curator_confirmed: WBPerson712
          Life_stage: WBls:0000056 PATO:0000460 Paper_evidence: WBPaper00028730
                Curator_confirmed: WBPerson712
          GO_term: GO:0005634 PATO:0000460 Paper_evidence: WBPaper00028730
                Curator_confirmed: WBPerson712
      WBPhenotype:0000682 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: XX animals completely feminized, XO animals fertile males, slightly feminized; e2020/+ XX also female Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Dominant: Person_evidence: WBPerson261
          Curator_confirmed: WBPerson712
        Variation_effect: Hypermorph_gain_of_function: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
  Reference: WBPaper00028730
    WBPaper00016482
    WBPaper00015242
    WBPaper00016310
    WBPaper00020776
  Method: Deletion_allele