WormBase Tree Display for Variation: WBVar00144477
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| WBVar00144477 | Name | Public_name | e2008 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Sequence_details | SeqStatus | Pending_curation | |||||||
| Variation_type | Allele | ||||||||
| Origin | Species | Caenorhabditis elegans | |||||||
| Strain | WBStrain00004532 | ||||||||
| WBStrain00004569 | |||||||||
| WBStrain00004571 | |||||||||
| WBStrain00004609 | |||||||||
| WBStrain00004629 | |||||||||
| Laboratory | CB | ||||||||
| Status | Live | ||||||||
| Affects | Gene | WBGene00004880 | |||||||
| Interactor | WBInteraction000519065 | ||||||||
| WBInteraction000519082 | |||||||||
| Genetics | Gene_class | sup | |||||||
| Mapping_data | In_2_point | 2503 | |||||||
| 2504 | |||||||||
| In_multi_point | 979 | ||||||||
| Description | Phenotype | WBPhenotype:0000506 | Paper_evidence | WBPaper00000922 | |||||
| Person_evidence | WBPerson261 | ||||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPerson712 | |||||||||
| Remark | adult male has swollen bursa | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| EQ_annotations | Life_stage | WBls:0000056 | PATO:0000460 | Paper_evidence | WBPaper00000922 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Ease_of_scoring | ES3_Easy_to_score | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000508 | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | unc-54 nonsense RNAs accumulate | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000697 | Paper_evidence | WBPaper00000922 | |||||||
| Person_evidence | WBPerson261 | ||||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPerson712 | |||||||||
| Remark | Adult hermaphrodite has protruding vulva, difficult to score (ES2). | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| EQ_annotations | Life_stage | WBls:0000041 | PATO:0000460 | Paper_evidence | WBPaper00000922 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0001538 | Paper_evidence | WBPaper00001192 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | Isolated as a suppressor of tra-3(e1767). Suppresses paralysis in unc-54(r293), sterility in tra-2(e1209), Egl and alae defects in lin-29(n546) and Dpy phenotype in dpy-5(e61) | Paper_evidence | WBPaper00001192 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00001192 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0001828 | Paper_evidence | WBPaper00004325 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | Mutant smg-2 animals recovered rapidly from unc-54 RNAi-induced paralysis, unlike wild-type | Paper_evidence | WBPaper00004325 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Phenotype_assay | Treatment | RNAi injection | Paper_evidence | WBPaper00004325 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Phenotype_not_observed | WBPhenotype:0001827 | Paper_evidence | WBPaper00004325 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | SMG-2 does not seem to affect RNAi by altering the editing or stability of dsRNA | Paper_evidence | WBPaper00004325 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Phenotype_assay | Treatment | Sequencing cDNAs derived from injected dsRNA. Decay profile of dsRNA in smg-2 | Paper_evidence | WBPaper00004325 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Reference | WBPaper00013926 | ||||||||
| WBPaper00013705 | |||||||||
| WBPaper00016504 | |||||||||
| WBPaper00004325 | |||||||||
| WBPaper00000922 | |||||||||
| WBPaper00013780 | |||||||||
| WBPaper00001192 | |||||||||
| WBPaper00013745 | |||||||||
| WBPaper00014435 | |||||||||
| WBPaper00014478 | |||||||||
| Method | Allele |
