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WormBase Tree Display for Variation: WBVar00144475

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Name Class

WBVar00144475NamePublic_namee2006
Sequence_detailsSeqStatusPending_curation
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00004512
LaboratoryCB
StatusLive
AffectsGeneWBGene00001413
InteractorWBInteraction000519741
WBInteraction000519742
GeneticsMapping_dataIn_multi_point3433
DescriptionPhenotypeWBPhenotype:0000006Paper_evidenceWBPaper00000922
Curator_confirmedWBPerson2021
RecessivePaper_evidenceWBPaper00000922
Curator_confirmedWBPerson2021
EQ_annotationsLife_stageWBls:0000041PATO:0000460Paper_evidenceWBPaper00000922
Curator_confirmedWBPerson2021
Maternal
WBPhenotype:0000038Paper_evidenceWBPaper00000922
Curator_confirmedWBPerson2021
RemarkIntersex XO animals are frequently ruptured at vulvaPaper_evidenceWBPaper00000922
Curator_confirmedWBPerson2021
RecessivePaper_evidenceWBPaper00000922
Curator_confirmedWBPerson2021
EQ_annotationsAnatomy_termWBbt:0006748PATO:0000460Paper_evidenceWBPaper00000922
Curator_confirmedWBPerson2021
Life_stageWBls:0000041PATO:0000460Paper_evidenceWBPaper00000922
Curator_confirmedWBPerson2021
Temperature_sensitiveHeat_sensitive25Paper_evidenceWBPaper00000922
Curator_confirmedWBPerson2021
Maternal
Phenotype_assayTemperature15C, 25CPaper_evidenceWBPaper00000922
Curator_confirmedWBPerson2021
WBPhenotype:0000050Paper_evidenceWBPaper00035459
Curator_confirmedWBPerson2021
Remarkfem-3(e2006) single-mutant animals exhibited a significant degree of embryonic lethalityPaper_evidenceWBPaper00035459
Curator_confirmedWBPerson2021
WBPhenotype:0000687Paper_evidenceWBPaper00000922
Person_evidenceWBPerson261
Curator_confirmedWBPerson2021
WBPerson712
RemarkXX animals are transformed into females at 25C. XO animals are intersexes with partial vulval development at 25C. The temperature-sensitive period (TSP) for e2006 begins in mid-L2 stage and persists into adulthood. Hermaphrodites often have masculinized tailsPaper_evidenceWBPaper00000922
Curator_confirmedWBPerson2021
XX self-fertile at 20CPerson_evidenceWBPerson261
Curator_confirmedWBPerson712
RecessivePaper_evidenceWBPaper00000922
Curator_confirmedWBPerson2021
EQ_annotationsLife_stageWBls:0000041PATO:0000460Paper_evidenceWBPaper00000922
Curator_confirmedWBPerson2021
Temperature_sensitiveHeat_sensitive25Paper_evidenceWBPaper00000922
Curator_confirmedWBPerson2021
Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Maternal
Phenotype_assayTemperature15C, 25CPaper_evidenceWBPaper00000922
Curator_confirmedWBPerson2021
WBPhenotype:0001355Paper_evidenceWBPaper00000922
Curator_confirmedWBPerson2021
RemarkMales have feminized gonadsPaper_evidenceWBPaper00000922
Curator_confirmedWBPerson2021
RecessivePaper_evidenceWBPaper00000922
Curator_confirmedWBPerson2021
EQ_annotationsLife_stageWBls:0000056PATO:0000460Paper_evidenceWBPaper00000922
Curator_confirmedWBPerson2021
Maternal
Phenotype_assayTemperature15CPaper_evidenceWBPaper00000922
Curator_confirmedWBPerson2021
Phenotype_not_observedWBPhenotype:0001182Paper_evidenceWBPaper00032310
Curator_confirmedWBPerson2987
Remarkfem-3(e2006ts) mutants exhibited normal fat content at the nonpermissive temperature, compared to wild type controls, as determined by Nile Red staining (Figure 2A-D)Paper_evidenceWBPaper00032310
Curator_confirmedWBPerson2987
ReferenceWBPaper00032310
WBPaper00000922
WBPaper00012683
WBPaper00035459
WBPaper00065793
MethodAllele