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WormBase Tree Display for Variation: WBVar00144378

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Name Class

WBVar00144378NamePublic_namee1880
Sequence_detailsSeqStatusPending_curation
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00004488
LaboratoryCB
StatusLive
AffectsGeneWBGene00000248
DescriptionPhenotypeWBPhenotype:0000011Paper_evidenceWBPaper00039901
Curator_confirmedWBPerson712
RemarkTreatment of ben-1(e1880) mutant embryos with nocodazole did not cause a 2AWC-ON phenotype as it does in controls. | Expression of wild-type ben-1 gene primarily in AWC using an odr-3 promoter restored the susceptibility of ben-1(e1880) mutants to nocodazole in the generation of 2AWC-ON phenotype.Paper_evidenceWBPaper00039901
Curator_confirmedWBPerson712
Variation_effectProbable_null_via_phenotypePaper_evidenceWBPaper00039901
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00004581Paper_evidenceWBPaper00039901
Curator_confirmedWBPerson712
EQ_annotationsAnatomy_termWBbt:0005672PATO:0000460Paper_evidenceWBPaper00039901
Curator_confirmedWBPerson712
Phenotype_assayGenotype[str-2p::GFP]Paper_evidenceWBPaper00039901
Curator_confirmedWBPerson712
WBPhenotype:0001854Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Remarkresistant to 14uM benomyl, no other phenotypePerson_evidenceWBPerson261
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00002892Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Ease_of_scoringES1_Very_hard_to_scorePerson_evidenceWBPerson261
Curator_confirmedWBPerson712
Phenotype_not_observedWBPhenotype:0000717Paper_evidenceWBPaper00039901
Curator_confirmedWBPerson712
Remarkben-1(e1880) mutants showed wild-type expression of str-2.Paper_evidenceWBPaper00039901
Curator_confirmedWBPerson712
Variation_effectProbable_null_via_phenotypePaper_evidenceWBPaper00039901
Curator_confirmedWBPerson712
EQ_annotationsAnatomy_termWBbt:0005672PATO:0000460Paper_evidenceWBPaper00039901
Curator_confirmedWBPerson712
Phenotype_assayGenotype[str-2p::GFP]Paper_evidenceWBPaper00039901
Curator_confirmedWBPerson712
WBPhenotype:0001853Paper_evidenceWBPaper00035150
Curator_confirmedWBPerson2021
RemarkMutant response to AAD 1470 was comparable to that observed in wild-typePaper_evidenceWBPaper00035150
Curator_confirmedWBPerson2021
ReferenceWBPaper00039901
WBPaper00035150
WBPaper00016120
MethodAllele