WormBase Tree Display for Variation: WBVar00144320

WBVar00144320 Name: Public_name: e1809
  Sequence_details: SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00004475
      WBStrain00056585
      WBStrain00056586
    Laboratory: CB
      CZ
    Status: Live
  Affects: Gene: WBGene00018051
  Genetics: Mapping_data: In_2_point: 789
      In_multi_point: 721
        3047
  Description: Phenotype: WBPhenotype:0000249 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: defective osmotic avoidance Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000615 Paper_evidence: WBPaper00000932
          WBPaper00045598
        Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: Amphid cilia absent, dendrites bulb-shaped, rare normal cilia. Mechanocilia rootlets abnormal. Paper_evidence: WBPaper00000932
            Curator_confirmed: WBPerson712
          striated ciliary rootlets missing from OLQ, IL1, BAG sensory neurons Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
          Mutations have abnormal cilia. Paper_evidence: WBPaper00045598
            Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0006848 PATO:0000460 Person_evidence: WBPerson261
                Curator_confirmed: WBPerson712
            WBbt:0005118 PATO:0000460 Person_evidence: WBPerson261
                Curator_confirmed: WBPerson712
            WBbt:0006825 PATO:0000460 Person_evidence: WBPerson261
                Curator_confirmed: WBPerson712
      WBPhenotype:0000637 Paper_evidence: WBPaper00000932
        Curator_confirmed: WBPerson712
        Remark: Intermediate response to dauer inducing conditions as assayed by SDS resistance of animals on crowded starved plate. Paper_evidence: WBPaper00000932
            Curator_confirmed: WBPerson712
      WBPhenotype:0000843 Paper_evidence: WBPaper00000932
        Curator_confirmed: WBPerson712
        Remark: Mating efficiency 0; no detected mating. Paper_evidence: WBPaper00000932
            Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000056 PATO:0000460 Paper_evidence: WBPaper00000932
                Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: him-5(e1490) Paper_evidence: WBPaper00000932
              Curator_confirmed: WBPerson712
      WBPhenotype:0001084 Paper_evidence: WBPaper00000932
        Curator_confirmed: WBPerson712
        Remark: Intermediate response to dilute gradient of NaCl. Paper_evidence: WBPaper00000932
            Curator_confirmed: WBPerson712
      WBPhenotype:0001414 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: males impotent Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0001765 Paper_evidence: WBPaper00031936
          WBPaper00045598
        Curator_confirmed: WBPerson2021
          WBPerson712
        Remark: Acute CO2 avoidance is eliminated Paper_evidence: WBPaper00031936
            Curator_confirmed: WBPerson2021
          Mutations have abnormal cilia as well as defective CO2 avoidance. Paper_evidence: WBPaper00045598
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00003023 Paper_evidence: WBPaper00045598
              Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00031936
                Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: 10% CO2 Paper_evidence: WBPaper00031936
              Curator_confirmed: WBPerson2021
      WBPhenotype:0002053 Paper_evidence: WBPaper00055368
        Curator_confirmed: WBPerson466
        Affected_by: Molecule: WBMol:00002786 Paper_evidence: WBPaper00055368
              Curator_confirmed: WBPerson466
      WBPhenotype:0002535 Paper_evidence: WBPaper00002087
          WBPaper00000932
        Person_evidence: WBPerson261
        Curator_confirmed: WBPerson48
          WBPerson712
        Remark: Defects in dye filling. Paper_evidence: WBPaper00002087
            Curator_confirmed: WBPerson48
          Frequent FITC staining of ADF and ADL but not other amphids or phasmids. Paper_evidence: WBPaper00000932
            Curator_confirmed: WBPerson712
          Dyf (no FITC uptake by amphids or phasmids) Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00002087
          Curator_confirmed: WBPerson48
        Ease_of_scoring: ES1_Very_hard_to_score: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0000315 Paper_evidence: WBPaper00000932
        Curator_confirmed: WBPerson712
      WBPhenotype:0000478 Paper_evidence: WBPaper00000932
        Curator_confirmed: WBPerson712
      WBPhenotype:0000505 Paper_evidence: WBPaper00000932
        Curator_confirmed: WBPerson712
        Remark: No FITC staining of ray sensilla. Paper_evidence: WBPaper00000932
            Curator_confirmed: WBPerson712
      WBPhenotype:0001285 Paper_evidence: WBPaper00045598
        Curator_confirmed: WBPerson712
        Remark: Mutants show a significant reduction in pumping following exposure to 10% CO2, similar to the reduction observed in wild-type (N2) animals Paper_evidence: WBPaper00045598
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00003023 Paper_evidence: WBPaper00045598
              Curator_confirmed: WBPerson712
      WBPhenotype:0001438 Paper_evidence: WBPaper00001786
        Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00001786
                Curator_confirmed: WBPerson2021
      WBPhenotype:0001530 Paper_evidence: WBPaper00000932
        Curator_confirmed: WBPerson712
        Remark: No FITC staining of CEP. Paper_evidence: WBPaper00000932
            Curator_confirmed: WBPerson712
      WBPhenotype:0001535 Paper_evidence: WBPaper00000932
        Curator_confirmed: WBPerson712
        Remark: No FITC of ADE or PDE. Paper_evidence: WBPaper00000932
            Curator_confirmed: WBPerson712
      WBPhenotype:0001660 Paper_evidence: WBPaper00006052
        Curator_confirmed: WBPerson2021
        Remark: No disruption of ASE asymmetry (as seen with lim-6 reporters) Paper_evidence: WBPaper00006052
            Curator_confirmed: WBPerson2021
        Variation_effect: Probable_null_via_phenotype: Paper_evidence: WBPaper00006052
            Curator_confirmed: WBPerson2021
        Phenotype_assay: Genotype: otIs114, otIs6 Paper_evidence: WBPaper00006052
              Curator_confirmed: WBPerson2021
  Reference: WBPaper00000932
    WBPaper00031936
    WBPaper00029016
    WBPaper00006052
    WBPaper00002087
    WBPaper00001786
    WBPaper00045598
    WBPaper00055368
    WBPaper00064927
    WBPaper00065994
  Method: Allele