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WormBase Tree Display for Variation: WBVar00144150

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Name Class

WBVar00144150NamePublic_namee1611
Sequence_detailsSeqStatusPending_curation
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00004360
WBStrain00052611
LaboratoryCB
StatusLive
AffectsGeneWBGene00003168
InteractorWBInteraction000005109
GeneticsMapping_dataIn_multi_point426
DescriptionPhenotypeWBPhenotype:0000179Paper_evidenceWBPaper00000502
Person_evidenceWBPerson261
Curator_confirmedWBPerson712
RemarkCells become vacuolated and die.Paper_evidenceWBPaper00000502
Curator_confirmedWBPerson712
microtubule cells become vacuolated and die in e1611 and e1611/+Person_evidenceWBPerson261
Curator_confirmedWBPerson712
DominantPaper_evidenceWBPaper00000502
Curator_confirmedWBPerson712
Variation_effectNeomorph_gain_of_functionPerson_evidenceWBPerson261
Curator_confirmedWBPerson712
EQ_annotationsAnatomy_termWBbt:0005237PATO:0000460Person_evidenceWBPerson261
Curator_confirmedWBPerson712
WBPhenotype:0000315Paper_evidenceWBPaper00001125
WBPaper00053740
Curator_confirmedWBPerson712
WBPerson31209
Remarkresponse to ultrasound stimulation significantly different from wild-type.Paper_evidenceWBPaper00053740
Curator_confirmedWBPerson31209
DominantPaper_evidenceWBPaper00001125
Curator_confirmedWBPerson712
WBPhenotype:0000456Paper_evidenceWBPaper00000502
Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Remarktouch insensitivePerson_evidenceWBPerson261
Curator_confirmedWBPerson712
DominantPaper_evidenceWBPaper00000502
Curator_confirmedWBPerson712
Variation_effectNeomorph_gain_of_functionPerson_evidenceWBPerson261
Curator_confirmedWBPerson712
Ease_of_scoringES2_Difficult_to_scorePerson_evidenceWBPerson261
Curator_confirmedWBPerson712
WBPhenotype:0000523Paper_evidenceWBPaper00038487
Curator_confirmedWBPerson712
RemarkWhile N2 animals traveling perpendicular to the NaCl attractant followed a path that curved with a bias toward the attractant, mutant animals did not regulate their turning; however, like wild-type animals curving decreased over time.Paper_evidenceWBPaper00038487
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00003571Paper_evidenceWBPaper00038487
Curator_confirmedWBPerson712
WBPhenotype:0004027Paper_evidenceWBPaper00038487
Curator_confirmedWBPerson712
RemarkAnimals exhibited lower escape responses (reversals) and smaller reversal sizes compared to N2 animals upon an initial plate tap, and no change in response to further taps applied at 10 second intervals.Paper_evidenceWBPaper00038487
Curator_confirmedWBPerson712
Phenotype_not_observedWBPhenotype:0000649Paper_evidenceWBPaper00003680
Curator_confirmedWBPerson712
Remarkmales are not defective in response or vulva locationPaper_evidenceWBPaper00003680
Curator_confirmedWBPerson712
WBPhenotype:0001273Paper_evidenceWBPaper00038142
Curator_confirmedWBPerson712
RemarkThe heat avoidance response in the mec-4(e1611) animals iscomparable to N2.Paper_evidenceWBPaper00038142
Curator_confirmedWBPerson712
WBPhenotype:0001715Paper_evidenceWBPaper00038487
Curator_confirmedWBPerson712
RemarkAnimals regulated pirouette-mediated reversals as a function of direction near food.Paper_evidenceWBPaper00038487
Curator_confirmedWBPerson712
WBPhenotype:0002000Paper_evidenceWBPaper00038487
Curator_confirmedWBPerson712
RemarkAfter exhibiting an increase in movement on food (induced by transferring a seeded plate to a multi-worm tracker (MWT) apparatus), the population of animals returned to their basal level of spontaneous locomotion speed on food at the same rate as N2 animals.Paper_evidenceWBPaper00038487
Curator_confirmedWBPerson712
WBPhenotype:0004004Paper_evidenceWBPaper00003680
Curator_confirmedWBPerson712
Remarkmales are not defective in response or vulva locationPaper_evidenceWBPaper00003680
Curator_confirmedWBPerson712
Reference (15)
MethodAllele