WormBase Tree Display for Variation: WBVar00144031

WBVar00144031 Name: Public_name: e1480
  Sequence_details: SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00004343
    Laboratory: CB
    Status: Live
  Affects: Gene: WBGene00001866
    Interactor: WBInteraction000520834
  Genetics: Mapping_data: In_2_point: 313
      In_multi_point: 288
  Description: Phenotype: WBPhenotype:0000050 Paper_evidence: WBPaper00000179
        Curator_confirmed: WBPerson712
        Remark: 34.1% eggs never hatch, yet are refractile; wild type animals produce 0.8% inviable zygotes. Paper_evidence: WBPaper00000179
            Curator_confirmed: WBPerson712
      WBPhenotype:0000154 Paper_evidence: WBPaper00000179
        Curator_confirmed: WBPerson712
        Remark: Animals have an average brood size of 19824 s.d. (6 broods counted), wild type has average brood size 33034 s.d. (8 broods counted). Paper_evidence: WBPaper00000179
            Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00000179
                Curator_confirmed: WBPerson712
      WBPhenotype:0000392 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: increased gut fluorescence bluish purple. Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Ease_of_scoring: ES1_Very_hard_to_score: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000863 Paper_evidence: WBPaper00000179
        Curator_confirmed: WBPerson712
        Remark: Males exhibit 32.3% wild type fertility. Paper_evidence: WBPaper00000179
            Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000056 PATO:0000460 Paper_evidence: WBPaper00000179
                Curator_confirmed: WBPerson712
      WBPhenotype:0001093 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: increased gut fluorescence bluish purple; low orthoaminophenol content low kynurenine hydroxylase. Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0001175 Paper_evidence: WBPaper00000565
          WBPaper00000179
        Curator_confirmed: WBPerson712
        Remark: Animals segregate 2.9% males compared to 0.3% segregated by wild type animals. Paper_evidence: WBPaper00000179
            Curator_confirmed: WBPerson712
      WBPhenotype:0001583 Paper_evidence: WBPaper00000179
        Curator_confirmed: WBPerson712
        Remark: Animals segregate a small percentage (1.0%) of short animals shown to be 3X hermaphrodites (wild type segregates 0.04% 3X herm.). Paper_evidence: WBPaper00000179
            Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00000179
                Curator_confirmed: WBPerson712
      WBPhenotype:0001631 Paper_evidence: WBPaper00000179
        Curator_confirmed: WBPerson712
        Remark: The sex ratio of cross progeny sired by him-7 males significantly differs from 1:1. Paper_evidence: WBPaper00000179
            Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000056 PATO:0000460 Paper_evidence: WBPaper00000179
                Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0000143 Paper_evidence: WBPaper00000565
        Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: UV sensitivities were measured as % survival based on radiation dose. Alkaline bleach isolated eggs ranging in age from 30-180 minutes were aliquoted to plates to give between 25-300 survivors/plate. The plated eggs were irradiated at different doses at a rate of 1Jm 10X-2/sec. Irradiated animals were protected from light. Survival was scored as the % animals reaching adulthood 4-6 days after irradiation relative to un-irradiated controls. Paper_evidence: WBPaper00000565
              Curator_confirmed: WBPerson712
      WBPhenotype:0000276 Paper_evidence: WBPaper00000565
        Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: X-ray sensitivities were measured as % survival based on radiation dose. Alkaline bleach isolated eggs ranging in age from 30-180 minutes were aliquoted to plates to give between 25-300 survivors/plate. The plated eggs were irradiated at different doses at a rate of 470 r/min. Survival was scored as the % animals reaching adulthood 4-6 days after irradiation relative to un-irradiated controls. Paper_evidence: WBPaper00000565
              Curator_confirmed: WBPerson712
      WBPhenotype:0000517 Paper_evidence: WBPaper00000179
        Curator_confirmed: WBPerson712
        Remark: Animals are indistinguishable from wild type in terms of behavior. Paper_evidence: WBPaper00000179
            Curator_confirmed: WBPerson712
      WBPhenotype:0000520 Paper_evidence: WBPaper00000179
        Curator_confirmed: WBPerson712
        Remark: Both hermaphrodites and males are indistinguishable from wild type in terms of superficial anatomy. Paper_evidence: WBPaper00000179
            Curator_confirmed: WBPerson712
      WBPhenotype:0000673 Paper_evidence: WBPaper00000565
        Curator_confirmed: WBPerson712
  Reference: WBPaper00000565
    WBPaper00016084
    WBPaper00000179
  Method: Allele