WormBase Tree Display for Variation: WBVar00144019

WBVar00144019 Name: Public_name: e1463
  Sequence_details: SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00033495
    Laboratory: CB
    Status: Live
  Affects: Gene: WBGene00006821
    Interactor: WBInteraction000518956
  Genetics: Mapping_data: In_2_point: 637
        677
        3655
        3656
        3657
      In_multi_point: 281
        553
        652
        1344
        1345
        2262
      In_pos_neg_data: 658
        660
        943
        1837
        1841
  Description: Phenotype: WBPhenotype:0000229 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: homozygotes small Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Ease_of_scoring: ES3_Easy_to_score: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000509 Paper_evidence: WBPaper00000536
        Curator_confirmed: WBPerson712
        Remark: Only 5.9% of sperm have pseudopods, all of which have normal morphology; sperm were from hemizygous males. Paper_evidence: WBPaper00000536
            Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0006798 PATO:0000460 Paper_evidence: WBPaper00000536
                Curator_confirmed: WBPerson712
      WBPhenotype:0000546 Paper_evidence: WBPaper00002305
        Curator_confirmed: WBPerson557
      WBPhenotype:0000553 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: abnormal muscle birefringence and ultrastructure Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000583 Paper_evidence: WBPaper00002305
        Curator_confirmed: WBPerson557
      WBPhenotype:0000634 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: abnormal pharyngeal pumping Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000643 Paper_evidence: WBPaper00002305
        Curator_confirmed: WBPerson557
        Remark: Severe locomotion defect. Paper_evidence: WBPaper00002305
            Curator_confirmed: WBPerson557
      WBPhenotype:0000644 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: paralysed (hypercontracted), heterozygote e1463/+ is slowish Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000688 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: homozygotes mostly sterile (not viable) Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0002019 Paper_evidence: WBPaper00002305
        Curator_confirmed: WBPerson557
      WBPhenotype:0002131 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: abnormal muscle birefringence and ultrastructure; heterozygote e1463/+ has muscle disorganization similar to but weaker than homozygote. Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
          heterozygote e1463/+ is somewhat dumpy Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Semi_dominant: Person_evidence: WBPerson261
          Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0001645 Paper_evidence: WBPaper00040284
        Curator_confirmed: WBPerson2987
        Remark: Table S2 Paper_evidence: WBPaper00040284
            Curator_confirmed: WBPerson2987
  Reference: WBPaper00040284
    WBPaper00000536
    WBPaper00030708
    WBPaper00002305
  Method: Allele