WormBase Tree Display for Variation: WBVar00143892

WBVar00143892 Evidence: Paper_evidence: WBPaper00004282
  Name: Public_name: e1287
    Other_name: F29C4.1b.1:c.605G>A
      F29C4.1a.1:c.605G>A
      CE17719:p.Trp202Ter
      CE31492:p.Trp202Ter
    HGVSg: CHROMOSOME_IV:g.135550G>A
  Sequence_details: SMap: S_parent: Sequence: F29C4
    Flanking_sequences: ccagaaaatcatgggaggcgaaattcgact gtatataagattcaagccaaaacctggaga
    Mapping_target: F29C4
    Type_of_mutation: Substitution: g a Paper_evidence: WBPaper00004282
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: CB
    Status: Live
  Affects: Gene: WBGene00000897
    Transcript: F29C4.1b.1 VEP_consequence: stop_gained
        VEP_impact: HIGH
        HGVSc: F29C4.1b.1:c.605G>A
        HGVSp: CE31492:p.Trp202Ter
        cDNA_position: 605
        CDS_position: 605
        Protein_position: 202
        Exon_number: 5/9
        Codon_change: tGg/tAg
        Amino_acid_change: W/*
      F29C4.1a.1 VEP_consequence: stop_gained
        VEP_impact: HIGH
        HGVSc: F29C4.1a.1:c.605G>A
        HGVSp: CE17719:p.Trp202Ter
        cDNA_position: 640
        CDS_position: 605
        Protein_position: 202
        Exon_number: 6/11
        Codon_change: tGg/tAg
        Amino_acid_change: W/*
    Interactor: WBInteraction000052156
      WBInteraction000500201
  Genetics: Interpolated_map_position: IV -26.9035
    Mapping_data: In_2_point: 408
  Description: Phenotype: WBPhenotype:0000012 Paper_evidence: WBPaper00028386
        Curator_confirmed: WBPerson712
        Remark: Animals formed less than 20% dauer at 16C. Paper_evidence: WBPaper00028386
            Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: 25 Paper_evidence: WBPaper00028386
              Curator_confirmed: WBPerson712
        Phenotype_assay: Temperature: 16 Paper_evidence: WBPaper00028386
              Curator_confirmed: WBPerson712
          Genotype: unc-4(e120) Paper_evidence: WBPaper00028386
              Curator_confirmed: WBPerson712
      WBPhenotype:0001837 Paper_evidence: WBPaper00050676
        Curator_confirmed: WBPerson20840
        Remark: does not respond to dietary restriction Paper_evidence: WBPaper00050676
            Curator_confirmed: WBPerson20840
        EQ_annotations: Life_stage: WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00050676
                Curator_confirmed: WBPerson20840
    Phenotype_not_observed: WBPhenotype:0002535 Paper_evidence: WBPaper00000932
        Curator_confirmed: WBPerson712
        Remark: FITC uptake is normal. Paper_evidence: WBPaper00000932
            Curator_confirmed: WBPerson712
  Reference: WBPaper00000932
    WBPaper00028386
    WBPaper00050676
  Method: Substitution_allele