Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Variation: WBVar00143821

expand all nodes | collapse all nodes | view schema

Name Class

WBVar00143821EvidencePaper_evidenceWBPaper00004275
NamePublic_namee1196
Other_nameJC8.10b.1:c.2194dup
CE28239:p.Asp726GlyfsTer2
CE29050:p.Asp732GlyfsTer2
JC8.10a.1:c.2176dup
HGVSgCHROMOSOME_IV:g.13265305_13265306insC
Sequence_detailsSMapS_parentSequenceJC8
Flanking_sequencesatttcaactatcgaattaatttgtcgggggatgaagttaagaatgctgttagaaatggag
Mapping_targetJC8
Type_of_mutationInsertiong
SeqStatusSequenced
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00004267
LaboratoryCB
StatusLive
AffectsGeneWBGene00006763
Transcript (2)
GeneticsInterpolated_map_positionIV8.51247
DescriptionPhenotypeWBPhenotype:0000017Paper_evidenceWBPaper00004275
Curator_confirmedWBPerson712
RemarkStrong allele. unc-26 mutants are strongly resistant to inhibitors of acetylcholinesterase, indicative of a decrease in acetylcholine release.Paper_evidenceWBPaper00004275
Curator_confirmedWBPerson712
WBPhenotype:0000210Paper_evidenceWBPaper00004275
Curator_confirmedWBPerson712
RemarkStrong allele. unc-26 mutants have reduced numbers of enteric muscle contractions, indicative of GABAergic function.Paper_evidenceWBPaper00004275
Curator_confirmedWBPerson712
WBPhenotype:0000229Paper_evidenceWBPaper00004275
Curator_confirmedWBPerson712
RemarkStrong allele. unc-26 mutants resemble mutants lacking the biosynthetic enzyme for acetylcholine encoded by the cha-1 gene; animals are small.Paper_evidenceWBPaper00004275
Curator_confirmedWBPerson712
WBPhenotype:0000455Paper_evidenceWBPaper00004275
Curator_confirmedWBPerson712
RemarkStrong allele. unc-26 mutants resemble mutants lacking the biosynthetic enzyme for acetylcholine encoded by the cha-1 gene; animals move backwards with a jerky motion.Paper_evidenceWBPaper00004275
Curator_confirmedWBPerson712
WBPhenotype:0000565Paper_evidenceWBPaper00004275
Curator_confirmedWBPerson712
RemarkStrong allele. unc-26 mutants resemble mutants lacking the biosynthetic enzyme for acetylcholine encoded by the cha-1 gene; frequently coil.Paper_evidenceWBPaper00004275
Curator_confirmedWBPerson712
WBPhenotype:0000631Paper_evidenceWBPaper00035198
Curator_confirmedWBPerson712
RemarkAnimals exhibit anterior convulsions when treated with pentylenetetrazole(PTZ).Paper_evidenceWBPaper00035198
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00004251Paper_evidenceWBPaper00035198
Curator_confirmedWBPerson712
ReferenceWBPaper00035198
WBPaper00014864
WBPaper00004275
WBPaper00015216
WBPaper00013791
MethodInsertion_allele