WormBase Tree Display for Variation: WBVar00143738

WBVar00143738 Evidence: Paper_evidence: WBPaper00003994
  Name: Public_name: e1096
    HGVSg: CHROMOSOME_III:g.11377892_11378667del
  Sequence_details: SMap: S_parent: Sequence: Y47D3B
    Flanking_sequences: tatgggcttgagttatatttctctaaccct aaactgaaagaaatattccgaaaatccttg
    Mapping_target: Y47D3B
    Type_of_mutation: Deletion
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00004397
    Laboratory: CB
    Status: Live
  Affects: Gene: WBGene00001077
    Transcript: Y47D3B.10.1 VEP_consequence: coding_sequence_variant,5_prime_UTR_variant
        VEP_impact: MODIFIER
        cDNA_position: ?-89
        CDS_position: ?-88
        Protein_position: ?-30
        Exon_number: 1-2/9
  Genetics: Interpolated_map_position: III 8.89472
  Description: Phenotype: WBPhenotype:0000505 Paper_evidence: WBPaper00001328
        Curator_confirmed: WBPerson712
        Remark: Homozygous Ram. Males are not Ram at 16C. Paper_evidence: WBPaper00001328
            Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0006941 PATO:0000460 Paper_evidence: WBPaper00001328
                Curator_confirmed: WBPerson712
          Life_stage: WBls:0000056 PATO:0000460 Paper_evidence: WBPaper00001328
                Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: 25 Paper_evidence: WBPaper00001328
              Curator_confirmed: WBPerson712
        Phenotype_assay: Temperature: 25C Paper_evidence: WBPaper00001328
              Curator_confirmed: WBPerson712
          Genotype: him-5(e1490) Paper_evidence: WBPaper00001328
              Curator_confirmed: WBPerson712
      WBPhenotype:0000583 Paper_evidence: WBPaper00001328
        Curator_confirmed: WBPerson712
        Phenotype_assay: Temperature: 20C Paper_evidence: WBPaper00001328
              Curator_confirmed: WBPerson712
          Genotype: him-5(e1490) Paper_evidence: WBPaper00001328
              Curator_confirmed: WBPerson712
      WBPhenotype:0001678 Paper_evidence: WBPaper00003994
        Curator_confirmed: WBPerson557
        Remark: There was a significant reduction in the hydroxyproline content of cuticle collagen from dpy-18 (e1096) animals compared with wild-type cuticle extracts. Paper_evidence: WBPaper00003994
            Curator_confirmed: WBPerson557
    Phenotype_not_observed: WBPhenotype:0000648 Paper_evidence: WBPaper00001328
        Curator_confirmed: WBPerson712
        Remark: Ray function was not severely disrupted by the morphological defects as most Ram males mated efficiently Paper_evidence: WBPaper00001328
            Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000056 PATO:0000460 Paper_evidence: WBPaper00001328
                Curator_confirmed: WBPerson712
        Phenotype_assay: Temperature: 20C Paper_evidence: WBPaper00001328
              Curator_confirmed: WBPerson712
          Genotype: him-5(e1490) Paper_evidence: WBPaper00001328
              Curator_confirmed: WBPerson712
      WBPhenotype:0000695 Paper_evidence: WBPaper00001328
        Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0006748 PATO:0000460 Paper_evidence: WBPaper00001328
                Curator_confirmed: WBPerson712
          Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00001328
                Curator_confirmed: WBPerson712
        Phenotype_assay: Temperature: 20C Paper_evidence: WBPaper00001328
              Curator_confirmed: WBPerson712
          Genotype: him-5(e1490) Paper_evidence: WBPaper00001328
              Curator_confirmed: WBPerson712
  Reference: WBPaper00001328
    WBPaper00014010
    WBPaper00015683
    WBPaper00003994
  Method: Deletion_allele