WormBase Tree Display for Variation: WBVar00143722

WBVar00143722 Name: Public_name: e1072
    Other_name: e1072am
  Sequence_details: SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain (48)
    Laboratory: CB
      RAF
    Status: Live
  Affects: Gene: WBGene00006765
    Interactor: WBInteraction000556210
      WBInteraction000556213
  Genetics: Mapping_data: In_2_point (16)
      In_multi_point (67)
      In_pos_neg_data: 745
        754
        763
        2516
        5849
        7288
        8083
        8095
        8103
        8110
  Description: Phenotype: WBPhenotype:0000017 Paper_evidence: WBPaper00004310
        Curator_confirmed: WBPerson2021
        Remark: unc-29 mutants are strongly resistant to aldicarb Paper_evidence: WBPaper00004310
            Curator_confirmed: WBPerson2021
        Affected_by: Molecule: WBMol:00003650 Paper_evidence: WBPaper00004310
              Curator_confirmed: WBPerson2021
      WBPhenotype:0000421 Paper_evidence: WBPaper00000484
          WBPaper00004310
          WBPaper00027611
        Curator_confirmed: WBPerson2021
          WBPerson712
        Remark: unc-29 mutants are strongly resistant to levamisole Paper_evidence: WBPaper00004310
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00000484
          Curator_confirmed: WBPerson2021
        Affected_by: Molecule: WBMol:00004019 Paper_evidence: WBPaper00000484
                WBPaper00004310
                WBPaper00027611
              Curator_confirmed: WBPerson2021
                WBPerson712
        Phenotype_assay: Treatment: 1mM levamisole Paper_evidence: WBPaper00000484
              Curator_confirmed: WBPerson2021
      WBPhenotype:0000554 Paper_evidence: WBPaper00000484
        Curator_confirmed: WBPerson2021
        Remark: Mutants succumb to osmotic shock. Paper_evidence: WBPaper00000484
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00000484
          Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: 10mM HEPES (pH 7.0), 0.25 per cent TWEEN 20. Paper_evidence: WBPaper00000484
              Curator_confirmed: WBPerson2021
      WBPhenotype:0000643 Paper_evidence: WBPaper00000484
        Curator_confirmed: WBPerson2021
        Remark: No backward motion in L1 larvae. Newly hatched larvae can barely move forward. Adults have a mild Unc defect where the mutants move forward in a slow decayed sine wave. Paper_evidence: WBPaper00000484
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00000484
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000024 PATO:0000460 Paper_evidence: WBPaper00000484
                Curator_confirmed: WBPerson2021
            WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00000484
                Curator_confirmed: WBPerson2021
      WBPhenotype:0000782 Paper_evidence: WBPaper00041265
        Curator_confirmed: WBPerson557
        Remark: Adults have body-wall muscle with disorganized thick filaments. Paper_evidence: WBPaper00041265
            Curator_confirmed: WBPerson557
        Phenotype_assay: Treatment: Animals carried the GFP::MHC A transgene to mark thick filaments. Paper_evidence: WBPaper00041265
              Curator_confirmed: WBPerson557
      WBPhenotype:0001315 Paper_evidence: WBPaper00029130
        Curator_confirmed: WBPerson14391
        Remark: No levamisole-AChR activity observed in isolated muscle cells Paper_evidence: WBPaper00029130
            Curator_confirmed: WBPerson14391
      WBPhenotype:0001645 Paper_evidence: WBPaper00004117
        Curator_confirmed: WBPerson1754
        Remark: Increased levels of protein degradation in muscle in response to starvation Paper_evidence: WBPaper00004117
            Curator_confirmed: WBPerson1754
    Phenotype_not_observed: WBPhenotype:0000315 Paper_evidence: WBPaper00000484
        Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00000484
          Curator_confirmed: WBPerson2021
      WBPhenotype:0000478 Paper_evidence: WBPaper00000484
        Curator_confirmed: WBPerson2021
        Remark: Mutants tend to remain within the borders of bacterial lawns as does the wild-type. Paper_evidence: WBPaper00000484
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00000484
          Curator_confirmed: WBPerson2021
      WBPhenotype:0000964 Paper_evidence: WBPaper00027611
        Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00000896 Paper_evidence: WBPaper00027611
              Curator_confirmed: WBPerson712
      WBPhenotype:0001084 Paper_evidence: WBPaper00000484
        Curator_confirmed: WBPerson2021
        Remark: Attraction to sodium chloride is normal (See methods). Paper_evidence: WBPaper00000484
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00000484
          Curator_confirmed: WBPerson2021
      WBPhenotype:0001232 Paper_evidence: WBPaper00001861
        Curator_confirmed: WBPerson712
        Remark: Male tail curling in reponse to serotonin is similar to WT Paper_evidence: WBPaper00001861
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00004929 Paper_evidence: WBPaper00001861
              Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000056 PATO:0000460 Paper_evidence: WBPaper00001861
                Curator_confirmed: WBPerson712
      WBPhenotype:0001414 Paper_evidence: WBPaper00000484
        Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00000484
          Curator_confirmed: WBPerson2021
      WBPhenotype:0001426 Paper_evidence: WBPaper00004883
        Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: arIs37 Paper_evidence: WBPaper00004883
              Curator_confirmed: WBPerson712
      WBPhenotype:0001645 Paper_evidence: WBPaper00040284
        Curator_confirmed: WBPerson2987
        Remark: Table S2 Paper_evidence: WBPaper00040284
            Curator_confirmed: WBPerson2987
      WBPhenotype:0001853 Paper_evidence: WBPaper00035150
        Curator_confirmed: WBPerson2021
        Remark: Mutant response to AAD 1470 was comparable to that observed in wild-type Paper_evidence: WBPaper00035150
            Curator_confirmed: WBPerson2021
  Reference (22)
  Remark
  Method: Allele