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WormBase Tree Display for Variation: WBVar00143717

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Name Class

WBVar00143717NamePublic_namee1065
Sequence_detailsSeqStatusPending_curation
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00004235
WBStrain00004394
WBStrain00004449
WBStrain00004450
WBStrain00004451
LaboratoryCB
StatusLive
AffectsGeneWBGene00001861
GeneticsMapping_dataIn_2_point265
In_multi_point36
DescriptionPhenotypeWBPhenotype:0000050Paper_evidenceWBPaper00000179
Curator_confirmedWBPerson712
Remark14.6% eggs never hatch, yet are refractile; wild type animals produce 0.8% inviable zygotes.Paper_evidenceWBPaper00000179
Curator_confirmedWBPerson712
WBPhenotype:0000154Paper_evidenceWBPaper00000179
Curator_confirmedWBPerson712
RemarkAnimals have an average brood size of 21756 s.d. (6 broods counted), wild type has average brood size 33034 s.d. (8 broods counted).Paper_evidenceWBPaper00000179
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000057PATO:0000460Paper_evidenceWBPaper00000179
Curator_confirmedWBPerson712
WBPhenotype:0000688Person_evidenceWBPerson261
Curator_confirmedWBPerson712
RemarkSome associated sterility.Person_evidenceWBPerson261
Curator_confirmedWBPerson712
WBPhenotype:0000863Paper_evidenceWBPaper00000179
Curator_confirmedWBPerson712
RemarkMales exhibit 23.5% wild type fertility.Paper_evidenceWBPaper00000179
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000056PATO:0000460Paper_evidenceWBPaper00000179
Curator_confirmedWBPerson712
WBPhenotype:0001175Paper_evidenceWBPaper00000565
WBPaper00000179
Person_evidenceWBPerson261
Curator_confirmedWBPerson712
RemarkMale self-progeny make up 1.6% of the population as measured from 8 broods, 956 total animals.Paper_evidenceWBPaper00000565
Curator_confirmedWBPerson712
Animals segregate 2.0% males compared to 0.3% segregated by wild type animals.Paper_evidenceWBPaper00000179
Curator_confirmedWBPerson712
self progeny 2% XO male; 1.5% ova are nullo-X; some associated sterility. Need to score for phenotype by analyzing progeny.Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Ease_of_scoringES2_Difficult_to_scorePerson_evidenceWBPerson261
Curator_confirmedWBPerson712
WBPhenotype:0001583Paper_evidenceWBPaper00000179
Curator_confirmedWBPerson712
RemarkAnimals segregate a small percentage (0.9%) of short animals shown to be 3X hermaphrodites (wild type segregates 0.04% 3X herm.).Paper_evidenceWBPaper00000179
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000057PATO:0000460Paper_evidenceWBPaper00000179
Curator_confirmedWBPerson712
Phenotype_not_observedWBPhenotype:0000143Paper_evidenceWBPaper00000565
Curator_confirmedWBPerson712
Phenotype_assayTreatmentUV sensitivities were measured as % survival based on radiation dose. Alkaline bleach isolated eggs ranging in age from 30-180 minutes were aliquoted to plates to give between 25-300 survivors/plate. The plated eggs were irradiated at different doses at a rate of 1Jm 10X-2/sec. Irradiated animals were protected from light. Survival was scored as the % animals reaching adulthood 4-6 days after irradiation relative to un-irradiated controls.Paper_evidenceWBPaper00000565
Curator_confirmedWBPerson712
WBPhenotype:0000276Paper_evidenceWBPaper00000565
Curator_confirmedWBPerson712
Phenotype_assayTreatmentX-ray sensitivities were measured as % survival based on radiation dose. Alkaline bleach isolated eggs ranging in age from 30-180 minutes were aliquoted to plates to give between 25-300 survivors/plate. The plated eggs were irradiated at different doses at a rate of 470 r/min. Survival was scored as the % animals reaching adulthood 4-6 days after irradiation relative to un-irradiated controls.Paper_evidenceWBPaper00000565
Curator_confirmedWBPerson712
WBPhenotype:0000517Paper_evidenceWBPaper00000179
Curator_confirmedWBPerson712
RemarkAnimals are indistinguishable from wild type in terms of behavior.Paper_evidenceWBPaper00000179
Curator_confirmedWBPerson712
WBPhenotype:0000520Paper_evidenceWBPaper00000179
Curator_confirmedWBPerson712
RemarkBoth hermaphrodites and males are indistinguishable from wild type in terms of superficial anatomy.Paper_evidenceWBPaper00000179
Curator_confirmedWBPerson712
WBPhenotype:0001631Paper_evidenceWBPaper00000179
Curator_confirmedWBPerson712
RemarkThe sex ratio of cross progeny sired by him males does not significantly differ from 1:1.Paper_evidenceWBPaper00000179
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000056PATO:0000460Paper_evidenceWBPaper00000179
Curator_confirmedWBPerson712
ReferenceWBPaper00000565
WBPaper00000179
WBPaper00014346
WBPaper00015999
WBPaper00013655
MethodAllele