WormBase Tree Display for Variation: WBVar00143109
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| WBVar00143109 | Evidence | Paper_evidence | WBPaper00004275 | ||||
|---|---|---|---|---|---|---|---|
| Name (3) | |||||||
| Sequence_details | SMap | S_parent | Sequence | Y67H2A | |||
| Flanking_sequences | ctggaatgggtggagcaactggaaataagg | atccgttgccttccgaatcgtcgtattctc | |||||
| Mapping_target | Y67H2A | ||||||
| Type_of_mutation | Substitution | g | a | Paper_evidence | WBPaper00004275 | ||
| SeqStatus | Sequenced | ||||||
| Variation_type | Allele | ||||||
| Origin | Species | Caenorhabditis elegans | |||||
| Laboratory | CB | ||||||
| Status | Live | ||||||
| Affects | Gene | WBGene00006763 | |||||
| Transcript | JC8.10b.1 (12) | ||||||
| JC8.10a.1 (12) | |||||||
| Genetics | Interpolated_map_position | IV | 8.51266 | ||||
| Description | Phenotype | WBPhenotype:0000017 | Paper_evidence | WBPaper00004275 | |||
| Curator_confirmed | WBPerson712 | ||||||
| Remark | Weak allele. unc-26 mutants are resistant to inhibitors of acetylcholinesterase, indicative of a decrease in acetylcholine release. | Paper_evidence | WBPaper00004275 | ||||
| Curator_confirmed | WBPerson712 | ||||||
| WBPhenotype:0000210 | Paper_evidence | WBPaper00004275 | |||||
| Curator_confirmed | WBPerson712 | ||||||
| Remark | Weak allele. unc-26 mutants have reduced numbers of enteric muscle contractions, indicative of GABAergic function. | Paper_evidence | WBPaper00004275 | ||||
| Curator_confirmed | WBPerson712 | ||||||
| WBPhenotype:0000229 | Paper_evidence | WBPaper00004275 | |||||
| Curator_confirmed | WBPerson712 | ||||||
| Remark | Weak allele. unc-26 mutants resemble mutants lacking the biosynthetic enzyme for acetylcholine encoded by the cha-1 gene; animals are small. | Paper_evidence | WBPaper00004275 | ||||
| Curator_confirmed | WBPerson712 | ||||||
| Strong allele. unc-26 mutants resemble mutants lacking the biosynthetic enzyme for acetylcholine encoded by the cha-1 gene; animals are small. | Paper_evidence | WBPaper00004275 | |||||
| Curator_confirmed | WBPerson712 | ||||||
| WBPhenotype:0000455 | Paper_evidence | WBPaper00004275 | |||||
| Curator_confirmed | WBPerson712 | ||||||
| Remark | Weak allele. unc-26 mutants resemble mutants lacking the biosynthetic enzyme for acetylcholine encoded by the cha-1 gene; animals move backwards with a jerky motion | Paper_evidence | WBPaper00004275 | ||||
| Curator_confirmed | WBPerson712 | ||||||
| WBPhenotype:0000565 | Paper_evidence | WBPaper00004275 | |||||
| Curator_confirmed | WBPerson712 | ||||||
| Remark | Weak allele. unc-26 mutants resemble mutants lacking the biosynthetic enzyme for acetylcholine encoded by the cha-1 gene; frequently coil. | Paper_evidence | WBPaper00004275 | ||||
| Curator_confirmed | WBPerson712 | ||||||
| WBPhenotype:0000643 | Paper_evidence | WBPaper00001303 | |||||
| Curator_confirmed | WBPerson712 | ||||||
| Remark | Animals showed good mobility throughout its life cycle. | Paper_evidence | WBPaper00001303 | ||||
| Curator_confirmed | WBPerson712 | ||||||
| Reference | WBPaper00021945 | ||||||
| WBPaper00004275 | |||||||
| WBPaper00013791 | |||||||
| WBPaper00001303 | |||||||
| Method | Substitution_allele |
