WormBase Tree Display for Variation: WBVar00143038
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| WBVar00143038 | Name | Public_name | e211 | |||||
|---|---|---|---|---|---|---|---|---|
| Sequence_details | SeqStatus | Pending_curation | ||||||
| Variation_type | Allele | |||||||
| Origin | Species | Caenorhabditis elegans | ||||||
| Strain | WBStrain00004129 | |||||||
| WBStrain00030691 | ||||||||
| Laboratory | CB | |||||||
| Status | Live | |||||||
| Affects | Gene | WBGene00002974 | ||||||
| Interactor | WBInteraction000518500 | |||||||
| WBInteraction000518501 | ||||||||
| WBInteraction000556207 | ||||||||
| Genetics | Mapping_data | In_multi_point | 1118 | |||||
| 2656 | ||||||||
| Description | Phenotype | WBPhenotype:0000421 | Paper_evidence | WBPaper00000484 | ||||
| WBPaper00035548 | ||||||||
| Curator_confirmed | WBPerson2021 | |||||||
| WBPerson712 | ||||||||
| Affected_by | Molecule | WBMol:00004019 | Paper_evidence | WBPaper00000484 | ||||
| Curator_confirmed | WBPerson2021 | |||||||
| Phenotype_assay | Treatment | 1mM levamisole | Paper_evidence | WBPaper00000484 | ||||
| Curator_confirmed | WBPerson2021 | |||||||
| WBPhenotype:0000643 | Paper_evidence | WBPaper00035548 | ||||||
| WBPaper00041959 | ||||||||
| Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | |||||||
| WBPerson557 | ||||||||
| Remark | Almost normal movement in absence of drug. | Person_evidence | WBPerson261 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| Exhibited significantly reduced general locomotor activity compared to control worms. | Paper_evidence | WBPaper00041959 | ||||||
| Curator_confirmed | WBPerson557 | |||||||
| WBPhenotype:0000845 | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | |||||||
| Remark | Uncoordinated but not hypercontracted in 1 mM levamisole. | Person_evidence | WBPerson261 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| Ease_of_scoring | ES2_Difficult_to_score | Person_evidence | WBPerson261 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| WBPhenotype:0001315 | Paper_evidence | WBPaper00029130 | ||||||
| Curator_confirmed | WBPerson14391 | |||||||
| Remark | Reduced conductance of levamisole-sensitive AChRs in muscle. Altered activation kinetics. | Paper_evidence | WBPaper00029130 | |||||
| Curator_confirmed | WBPerson14391 | |||||||
| WBPhenotype:0001645 | Paper_evidence | WBPaper00004117 | ||||||
| Curator_confirmed | WBPerson1754 | |||||||
| Remark | Increased levels of protein degradation in muscle in response to starvation | Paper_evidence | WBPaper00004117 | |||||
| Curator_confirmed | WBPerson1754 | |||||||
| Resistant to levamisole prevention of muscle protein degradation in response to starvation | Paper_evidence | WBPaper00004117 | ||||||
| Curator_confirmed | WBPerson1754 | |||||||
| WBPhenotype:0001852 | Paper_evidence | WBPaper00035074 | ||||||
| Curator_confirmed | WBPerson2021 | |||||||
| Remark | Mutants are resistant to tribendimidine | Paper_evidence | WBPaper00035074 | |||||
| Curator_confirmed | WBPerson2021 | |||||||
| WBPhenotype:0002256 | Paper_evidence | WBPaper00041069 | ||||||
| Curator_confirmed | WBPerson1754 | |||||||
| Remark | Increased sensitivity to movement decline in response to selenium exposure | Paper_evidence | WBPaper00041069 | |||||
| Curator_confirmed | WBPerson1754 | |||||||
| Affected_by | Molecule | WBMol:00001915 | Paper_evidence | WBPaper00041069 | ||||
| Curator_confirmed | WBPerson1754 | |||||||
| Phenotype_not_observed | WBPhenotype:0001853 | Paper_evidence | WBPaper00035150 | |||||
| Curator_confirmed | WBPerson2021 | |||||||
| Remark | Mutant response to AAD 1470 was comparable to that observed in wild-type | Paper_evidence | WBPaper00035150 | |||||
| Curator_confirmed | WBPerson2021 | |||||||
| Reference (11) | ||||||||
| Method | Allele |
