WormBase Tree Display for Variation: WBVar00094621

WBVar00094621 Evidence: Paper_evidence: WBPaper00004137
  Name: Public_name: om96
    Other_name: CE27140:p.His139Leu
      F26A3.3.1:c.416A>T
    HGVSg: CHROMOSOME_I:g.7655770T>A
  Sequence_details: SMap: S_parent: Sequence: F26A3
    Flanking_sequences: ctaacgtcatcccagaaagacacttcccaa gattaatgaatgttccgccttgaatatttc
    Mapping_target: F26A3
    Type_of_mutation: Substitution: t a Curator_confirmed: WBPerson4055
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: EL
    Status: Live
  Affects: Gene: WBGene00001214
    Transcript: F26A3.3.1 (12)
  Genetics: Interpolated_map_position: I 2.21486
  Description: Phenotype: WBPhenotype:0000812 Paper_evidence: WBPaper00004137
        Curator_confirmed: WBPerson2021
        Remark: Intersexual germ cells were only observed when the germ line switched from spermatogenesis to oogenesis Paper_evidence: WBPaper00004137
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00004137
          Curator_confirmed: WBPerson2021
        Variation_effect: Probable_null_via_phenotype: Paper_evidence: WBPaper00004137
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00004137
                Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: DAPI staining Paper_evidence: WBPaper00004137
              Curator_confirmed: WBPerson2021
      WBPhenotype:0001260 Paper_evidence: WBPaper00004137
        Curator_confirmed: WBPerson2021
        Remark: Mutants typically produced small oocytes with unusual chromosome morphology Paper_evidence: WBPaper00004137
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00004137
          Curator_confirmed: WBPerson2021
        Variation_effect: Probable_null_via_phenotype: Paper_evidence: WBPaper00004137
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00004137
                Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: DAPI staining Paper_evidence: WBPaper00004137
              Curator_confirmed: WBPerson2021
      WBPhenotype:0001694 Paper_evidence: WBPaper00004137
        Curator_confirmed: WBPerson2021
        Remark: The spermatogenesis-to-oogenesis switch occurred several hours later in ego-1 mutants than in controls Paper_evidence: WBPaper00004137
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00004137
          Curator_confirmed: WBPerson2021
        Variation_effect: Probable_null_via_phenotype: Paper_evidence: WBPaper00004137
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00004137
                Curator_confirmed: WBPerson2021
      WBPhenotype:0001945 Paper_evidence: WBPaper00004137
        Curator_confirmed: WBPerson557
        Remark: Mutants typically produced small oocytes with unusual chromosome morphology Paper_evidence: WBPaper00004137
            Curator_confirmed: WBPerson557
        Recessive: Paper_evidence: WBPaper00004137
          Curator_confirmed: WBPerson557
        Variation_effect: Probable_null_via_phenotype: Paper_evidence: WBPaper00004137
            Curator_confirmed: WBPerson557
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00004137
                Curator_confirmed: WBPerson557
        Phenotype_assay: Treatment: DAPI staining Paper_evidence: WBPaper00004137
              Curator_confirmed: WBPerson557
  Reference: WBPaper00004137
  Remark: Variation flanks and nucleotide change automatically updated to be on the positive strand to fix mapping and gff dumping issues.
    [200224 mh6] reverse complemented/swapped the change and flanks to move the variation onto the plus strand Curator_confirmed: WBPerson4055
  Method: Substitution_allele