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WormBase Tree Display for Variation: WBVar00093458

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Name Class

WBVar00093458NamePublic_nameok2300
Other_nameCE47965:p.Pro744_Ter1004delinsHisLeuLysAspSerGlu
CE48031:p.Pro744_Ter1004delinsHisLeuLysAspSerGlu
F11H8.4b.1:c.2231_3011delinsATCTGAAGGATTCCGA
F11H8.4a.1:c.2231_3011delinsATCTGAAGGATTCCGA
HGVSgCHROMOSOME_III:g.7025278_7026104delinsTCGGAATCCTTCAGAT
Sequence_detailsSMapS_parentSequenceF11H8
Flanking_sequencesttcaaaaatgttcggaatccttcagatgctgcgggggtcctccggtgattggaggaagac
Mapping_targetF11H8
Type_of_mutationInsertionTCGGAATCCTTCAGAT
Deletion
PCR_productOK2300_external
OK2300_internal
SeqStatusSequenced
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00036953
LaboratoryRB
PersonWBPerson46
KO_consortium_allele
StatusLive
AffectsGeneWBGene00000872
TranscriptF11H8.4b.1 (11)
F11H8.4a.1 (11)
InteractorWBInteraction000534801
IsolationMutagenEMS
DescriptionPhenotypeWBPhenotype:0000087Paper_evidenceWBPaper00041258
Curator_confirmedWBPerson3809
Remarkin worms rescued maternally for embryogenesis- thin body-wall muscle cellsPaper_evidenceWBPaper00041258
Curator_confirmedWBPerson3809
WBPhenotype:0000395Paper_evidenceWBPaper00041258
Curator_confirmedWBPerson3809
Remarkin worms rescued maternally for embryogenesis- small single-arm gonad with few to no mature gametes.Paper_evidenceWBPaper00041258
Curator_confirmedWBPerson3809
WBPhenotype:0000697Paper_evidenceWBPaper00041258
Curator_confirmedWBPerson3809
Remarkin worms rescued maternally for embryogenesis- protruding vulva (Pvl)Paper_evidenceWBPaper00041258
Curator_confirmedWBPerson3809
WBPhenotype:0001213Paper_evidenceWBPaper00041258
Curator_confirmedWBPerson3809
Remarkin worms rescued maternally for embryogenesis- slow body movementsPaper_evidenceWBPaper00041258
Curator_confirmedWBPerson3809
WBPhenotype:0001699Paper_evidenceWBPaper00041258
Curator_confirmedWBPerson3809
Remarkin worms rescued maternally for embryogenesis- body immobility in the middle/posteriorPaper_evidenceWBPaper00041258
Curator_confirmedWBPerson3809
WBPhenotype:0001889Paper_evidenceWBPaper00047037
Curator_confirmedWBPerson3809
RemarkWe examined body-wall muscle sarcomere structure in cyk-1(ok2300) and fhod-1(tm2363) adult hermaphrodites using TEM. Both single mutants and double mutants had sarcomeres that contained thin and thick filaments, but their sarcomeres were smaller than wild-type, and contained fewer thin and thick filaments than wild-type.Paper_evidenceWBPaper00047037
Curator_confirmedWBPerson3809
WBPhenotype:0001890Paper_evidenceWBPaper00047037
Curator_confirmedWBPerson3809
RemarkThe dense bodies of cyk-1(ok2300) and fhod-1(tm2363);cyk-1(ok2300) mutants were deficient in electron-dense material.Paper_evidenceWBPaper00047037
Curator_confirmedWBPerson3809
WBPhenotype:0002207Paper_evidenceWBPaper00041258
Curator_confirmedWBPerson3809
Remarkin worms rescued maternally for embryogenesis- small single-arm gonad with few to no mature gametes.Paper_evidenceWBPaper00041258
Curator_confirmedWBPerson3809
ReferenceWBPaper00041258
WBPaper00047037
RemarkSequenced by the C. elegans Gene Knockout ConsortiumPaper_evidenceWBPaper00041807
MethodKO_consortium_allele