WormBase Tree Display for Variation: WBVar00093318
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| WBVar00093318 | Name | Public_name | ok2140 | ||||
|---|---|---|---|---|---|---|---|
| Other_name | F25B3.1.1:c.725-158_1633-197del | ||||||
| HGVSg | CHROMOSOME_V:g.9551795_9553163del | ||||||
| Sequence_details | SMap | S_parent | Sequence | F25B3 | |||
| Flanking_sequences | aggaacatcgaaaatcgaaaaaaaaattcg | tacataactgaacatttcctactaccatat | |||||
| Mapping_target | F25B3 | ||||||
| Type_of_mutation | Deletion | ||||||
| PCR_product | ok2140_external | ||||||
| ok2140_internal | |||||||
| SeqStatus | Sequenced | ||||||
| Variation_type | Allele | ||||||
| Origin | Species | Caenorhabditis elegans | |||||
| Strain | WBStrain00036808 | ||||||
| Laboratory | RB | ||||||
| Person | WBPerson46 | ||||||
| KO_consortium_allele | |||||||
| Status | Live | ||||||
| Affects | Gene | WBGene00009098 | |||||
| Transcript | F25B3.1.1 | VEP_consequence | splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant | ||||
| VEP_impact | HIGH | ||||||
| HGVSc | F25B3.1.1:c.725-158_1633-197del | ||||||
| Intron_number | 4-6/14 | ||||||
| Exon_number | 5-6/15 | ||||||
| Isolation | Mutagen | EMS | |||||
| Description | Phenotype | WBPhenotype:0000384 | Paper_evidence | WBPaper00052994 | |||
| Curator_confirmed | WBPerson557 | ||||||
| Remark | Mutants showed significant defects in VD/DD axon pathfinding,including ectopic axon branching and wandering. | Paper_evidence | WBPaper00052994 | ||||
| Curator_confirmed | WBPerson557 | ||||||
| WBPhenotype:0000572 | Paper_evidence | WBPaper00052994 | |||||
| Curator_confirmed | WBPerson557 | ||||||
| Remark | VD growth cones in these mutants display increased filopodial protrusion, similar to mutants in repulsive UNC-6/Netrin signaling. | Paper_evidence | WBPaper00052994 | ||||
| Curator_confirmed | WBPerson557 | ||||||
| WBPhenotype:0000880 | Paper_evidence | WBPaper00052994 | |||||
| Curator_confirmed | WBPerson557 | ||||||
| Remark | VD growth cones in these mutants display increased filopodial protrusion, similar to mutants in repulsive UNC-6/Netrin signaling. | Paper_evidence | WBPaper00052994 | ||||
| Curator_confirmed | WBPerson557 | ||||||
| WBPhenotype:0002490 | Paper_evidence | WBPaper00052994 | |||||
| Curator_confirmed | WBPerson557 | ||||||
| Remark | Mutants showed significant defects in VD/DD axon pathfinding,including ectopic axon branching and wandering. | Paper_evidence | WBPaper00052994 | ||||
| Curator_confirmed | WBPerson557 | ||||||
| Reference | WBPaper00052994 | ||||||
| Remark | Sequenced by the C. elegans Gene Knockout Consortium | Paper_evidence | WBPaper00041807 | ||||
| Method | KO_consortium_allele |
