WormBase Tree Display for Variation: WBVar00092938

WBVar00092938 Name: Public_name: ok1735
    Other_name: CE49843:p.Thr35_Ter300delinsSerLeu
      K04G2.5b.1:c.103_900delinsTCTCTA
      K04G2.5a.4:c.-141_657delinsTCTCTA
      K04G2.5a.1:c.-141_657delinsTCTCTA
      K04G2.5a.3:c.-141_657delinsTCTCTA
    HGVSg: CHROMOSOME_I:g.8037199_8039137delinsTAGAGA
  Sequence_details: SMap: S_parent: Sequence: K04G2
    Flanking_sequences: GAATGAATTGAATATTTAGTGGGCAATGTG ctgtgtagagacggcagaagttacaataac
    Mapping_target: K04G2
    Type_of_mutation: Insertion: TAGAGA
      Deletion
    PCR_product: ok1735_external
      ok1735_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00032181
    Laboratory: RB
    Person: WBPerson46
    KO_consortium_allele
    Status: Live
  Affects: Gene: WBGene00010564
    Transcript: K04G2.5a.4 VEP_consequence: splice_acceptor_variant,splice_donor_variant,start_lost,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: K04G2.5a.4:c.-141_657delinsTCTCTA
        cDNA_position: 119-916
        CDS_position: ?-657
        Protein_position: ?-219
        Intron_number: 2-6/7
        Exon_number: 2-7/8
      K04G2.5b.1 (11)
      K04G2.5a.2 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        cDNA_position: ?-728
        CDS_position: ?-657
        Protein_position: ?-219
        Intron_number: 2-4/5
        Exon_number: 1-5/6
      K04G2.5a.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,start_lost,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: K04G2.5a.1:c.-141_657delinsTCTCTA
        cDNA_position: 45-842
        CDS_position: ?-657
        Protein_position: ?-219
        Intron_number: 1-5/6
        Exon_number: 1-6/7
      K04G2.5a.3 VEP_consequence: splice_acceptor_variant,splice_donor_variant,start_lost,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: K04G2.5a.3:c.-141_657delinsTCTCTA
        cDNA_position: 536-1333
        CDS_position: ?-657
        Protein_position: ?-219
        Intron_number: 2-6/7
        Exon_number: 2-7/8
  Isolation: Mutagen: EMS
  Genetics: Mapping_data: In_multi_point: 5616
  Description: Phenotype: WBPhenotype:0000039 Paper_evidence: WBPaper00045834
        Curator_confirmed: WBPerson2987
        Remark: ath-1(ok1735) mutants showed decreased time to 90% mortality (Table 2, Figure 4A) Paper_evidence: WBPaper00045834
            Curator_confirmed: WBPerson2987
    Phenotype_not_observed: WBPhenotype:0000315 Paper_evidence: WBPaper00045834
        Curator_confirmed: WBPerson2987
        Remark: Additional file 12 Paper_evidence: WBPaper00045834
            Curator_confirmed: WBPerson2987
      WBPhenotype:0000643 Paper_evidence: WBPaper00045834
        Curator_confirmed: WBPerson2987
        Remark: Animals did not show a significant difference in age-related decline of thrashing rate, compared to wild type (N2) controls (Additional file 9) Paper_evidence: WBPaper00045834
            Curator_confirmed: WBPerson2987
      WBPhenotype:0001700 Paper_evidence: WBPaper00045834
        Curator_confirmed: WBPerson2987
        Remark: Figure 3 A-B Paper_evidence: WBPaper00045834
            Curator_confirmed: WBPerson2987
      WBPhenotype:0001726 Paper_evidence: WBPaper00045834
        Curator_confirmed: WBPerson2987
        Remark: Wild-type N2 animals had an average length of 1222 μm and width of 78 μm (Additional file 6). Mutants for ath-1(ok1735) showed no significant changes in body length or width. Paper_evidence: WBPaper00045834
            Curator_confirmed: WBPerson2987
      WBPhenotype:0001727 Paper_evidence: WBPaper00045834
        Curator_confirmed: WBPerson2987
        Remark: Wild-type N2 animals had an average length of 1222 μm and width of 78 μm (Additional file 6). Mutants for ath-1(ok1735) showed no significant changes in body length or width. Paper_evidence: WBPaper00045834
            Curator_confirmed: WBPerson2987
      WBPhenotype:0004023 Paper_evidence: WBPaper00045834
        Curator_confirmed: WBPerson2987
        Remark: Additional file 8 Paper_evidence: WBPaper00045834
            Curator_confirmed: WBPerson2987
  Reference: WBPaper00045834
  Remark: Sequenced by the C. elegans Gene Knockout Consortium Paper_evidence: WBPaper00041807
  Method: KO_consortium_allele