WormBase Tree Display for Variation: WBVar00092775

WBVar00092775 Evidence: Paper_evidence: WBPaper00038249
  Name: Public_name: ok1566
  Sequence_details: PCR_product: OK1566_external
      OK1566_internal
    SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00032079
    Laboratory: RB
    Person: WBPerson46
    KO_consortium_allele
    Status: Live
  Affects: Gene: WBGene00009920
    Interactor: WBInteraction000501228
      WBInteraction000501229
      WBInteraction000517363
      WBInteraction000517364
      WBInteraction000517365
  Genetics: Mapping_data: In_multi_point: 5145
  Description: Phenotype: WBPhenotype:0000006 Paper_evidence: WBPaper00038249
        Curator_confirmed: WBPerson712
        Remark: Animals exhibit decreased egg production. Paper_evidence: WBPaper00038249
            Curator_confirmed: WBPerson712
        Penetrance: Incomplete: Paper_evidence: WBPaper00038249
              Curator_confirmed: WBPerson712
      WBPhenotype:0000324 Paper_evidence: WBPaper00038249
        Curator_confirmed: WBPerson712
        Remark: Mutants were modestly shorter than wild type animals. Paper_evidence: WBPaper00038249
            Curator_confirmed: WBPerson712
      WBPhenotype:0001703 Paper_evidence: WBPaper00038249
        Curator_confirmed: WBPerson712
        Remark: abts-1 mutants performed a lower number of body bends. Paper_evidence: WBPaper00038249
            Curator_confirmed: WBPerson712
      WBPhenotype:0001905 Paper_evidence: WBPaper00038249
        Curator_confirmed: WBPerson712
        Remark: abts-1 mutants lay fewer cumulative eggs than do wild-type animals. Paper_evidence: WBPaper00038249
            Curator_confirmed: WBPerson712
      WBPhenotype:0002047 Paper_evidence: WBPaper00038249
        Curator_confirmed: WBPerson712
        Remark: Mutants show excitatory rather than inhibitory responses to the GABA A agonist muscimol. Paper_evidence: WBPaper00038249
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00003906 Paper_evidence: WBPaper00038249
              Curator_confirmed: WBPerson712
      WBPhenotype:0002070 Paper_evidence: WBPaper00038249
        Curator_confirmed: WBPerson712
        Remark: Muscimol fails to inhibit egg laying in abts-1 mutants, whereas in control wild-type animals, muscimol inhibited egg laying by 97% over 2 hours. Paper_evidence: WBPaper00038249
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00003906 Paper_evidence: WBPaper00038249
              Curator_confirmed: WBPerson712
      WBPhenotype:0002071 Paper_evidence: WBPaper00038249
        Curator_confirmed: WBPerson712
        Remark: Mutants exposed to muscimol undergo a decrease in body length, whereas wild-type animals exposed to muscimol experience a significant increase in body length. Paper_evidence: WBPaper00038249
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00003906 Paper_evidence: WBPaper00038249
              Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0000546 Paper_evidence: WBPaper00038249
        Curator_confirmed: WBPerson712
      WBPhenotype:0000643 Paper_evidence: WBPaper00038249
        Curator_confirmed: WBPerson712
        Remark: These mutants show well-coordinated locomotion. Paper_evidence: WBPaper00038249
            Curator_confirmed: WBPerson712
  Reference: WBPaper00038249
  Remark: ok1566 is a 899bp deletion Paper_evidence: WBPaper00038249
  Method: KO_consortium_allele