WormBase Tree Display for Variation: WBVar00092214

WBVar00092214 Name: Public_name: ok943
    Other_name: C43E11.6b.1:c.560-69_1333del
      C43E11.6a.1:c.1040-69_1813del
      C43E11.6e.2:c.458-69_1231del
      C43E11.6e.3:c.458-69_1231del
      C43E11.6a.3:c.1040-69_1813del
      C43E11.6b.2:c.560-69_1333del
      C43E11.6c.1:c.*1050-69_*1823del
      C43E11.6d.1:c.851-69_1624del
      C43E11.6a.2:c.1040-69_1813del
      C43E11.6e.1:c.458-69_1231del
    HGVSg: CHROMOSOME_I:g.4233817_4234848del
  Sequence_details: SMap: S_parent: Sequence: C43E11
    Flanking_sequences: tacaccatattccgcgcaagcgtagagaaa gcaaacttctgttcccactccgaaagaagt
    Mapping_target: C43E11
    Type_of_mutation: Deletion
    PCR_product: ok943_external
      ok943_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00031725
    Laboratory: RB
    Person: WBPerson46
    KO_consortium_allele
    Status: Live
  Affects: Gene: WBGene00003516
    Transcript: C43E11.6e.2 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C43E11.6e.2:c.458-69_1231del
        cDNA_position: ?-1627
        CDS_position: ?-1231
        Protein_position: ?-411
        Intron_number: 6-7/9
        Exon_number: 7-8/10
      C43E11.6a.2 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C43E11.6a.2:c.1040-69_1813del
        cDNA_position: ?-1840
        CDS_position: ?-1813
        Protein_position: ?-605
        Intron_number: 8-9/11
        Exon_number: 9-10/12
      C43E11.6e.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C43E11.6e.1:c.458-69_1231del
        cDNA_position: ?-1435
        CDS_position: ?-1231
        Protein_position: ?-411
        Intron_number: 5-6/8
        Exon_number: 6-7/9
      C43E11.6d.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C43E11.6d.1:c.851-69_1624del
        cDNA_position: ?-1743
        CDS_position: ?-1624
        Protein_position: ?-542
        Intron_number: 8-9/11
        Exon_number: 9-10/12
      C43E11.6a.3 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C43E11.6a.3:c.1040-69_1813del
        cDNA_position: ?-1842
        CDS_position: ?-1813
        Protein_position: ?-605
        Intron_number: 8-9/12
        Exon_number: 9-10/13
      C43E11.6b.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C43E11.6b.1:c.560-69_1333del
        cDNA_position: ?-1459
        CDS_position: ?-1333
        Protein_position: ?-445
        Intron_number: 6-7/9
        Exon_number: 7-8/10
      C43E11.6b.2 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C43E11.6b.2:c.560-69_1333del
        cDNA_position: ?-1362
        CDS_position: ?-1333
        Protein_position: ?-445
        Intron_number: 5-6/8
        Exon_number: 6-7/9
      C43E11.6a.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C43E11.6a.1:c.1040-69_1813del
        cDNA_position: ?-1932
        CDS_position: ?-1813
        Protein_position: ?-605
        Intron_number: 9-10/12
        Exon_number: 10-11/13
      C43E11.6c.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C43E11.6c.1:c.*1050-69_*1823del
        cDNA_position: ?-2125
        Intron_number: 8-9/10
        Exon_number: 9-10/11
      C43E11.6e.3 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C43E11.6e.3:c.458-69_1231del
        cDNA_position: ?-1358
        CDS_position: ?-1231
        Protein_position: ?-411
        Intron_number: 4-5/7
        Exon_number: 5-6/8
    Interactor: WBInteraction000517452
      WBInteraction000517453
  Isolation: Mutagen: UV/TMP
  Description: Phenotype: WBPhenotype:0002232 Paper_evidence: WBPaper00028874
        Curator_confirmed: WBPerson4787
        Remark: synaptic remodeling defect. fail to remove synapses Paper_evidence: WBPaper00028874
            Curator_confirmed: WBPerson4787
    Phenotype_not_observed: WBPhenotype:0000616 Paper_evidence: WBPaper00028874
        Curator_confirmed: WBPerson4787
        Remark: normal synapse morphology Paper_evidence: WBPaper00028874
            Curator_confirmed: WBPerson4787
  Reference: WBPaper00028874
  Remark: Sequenced by the C. elegans Gene Knockout Consortium Paper_evidence: WBPaper00041807
  Method: KO_consortium_allele