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WormBase Tree Display for Variation: WBVar00090148

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Name Class

WBVar00090148NamePublic_namen1377
Sequence_detailsType_of_mutationDeletion
SeqStatusPending_curation
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00027040
WBStrain00030729
WBStrain00030730
WBStrain00030732
LaboratoryMT
StatusLive
AffectsGeneWBGene00001185
InteractorWBInteraction000535557
WBInteraction000556185
DescriptionPhenotypeWBPhenotype:0000006Paper_evidenceWBPaper00006107
Curator_confirmedWBPerson712
RemarkSM chemoattraction can be rescued by expression of LET-756.Paper_evidenceWBPaper00006107
Curator_confirmedWBPerson712
WBPhenotype:0000245Paper_evidenceWBPaper00006107
WBPaper00002741
Curator_confirmedWBPerson712
RemarkSM chemoattraction can be rescued by expression of LET-756.Paper_evidenceWBPaper00006107
Curator_confirmedWBPerson712
Isolated in a screen for severely displaced SMs in a wild-type background. Displays a distribution of posteriorly displaced SMs similar in all egl-17 alleles.Paper_evidenceWBPaper00002741
Curator_confirmedWBPerson712
WBPhenotype:0000640Paper_evidenceWBPaper00002741
Curator_confirmedWBPerson712
Remarkegl-17(n1377) is 83% penetrant for the Egl phenotype.Paper_evidenceWBPaper00002741
Curator_confirmedWBPerson712
PenetranceIncomplete83%Paper_evidenceWBPaper00002741
Curator_confirmedWBPerson712
WBPhenotype:0001645Paper_evidenceWBPaper00006119
Curator_confirmedWBPerson1754
Remarkn1377 and s2613 together, but not individually, block the protein degradation observed in clr-1(e1745)Paper_evidenceWBPaper00006119
Curator_confirmedWBPerson1754
Phenotype_not_observedWBPhenotype:0001645Paper_evidenceWBPaper00040284
Curator_confirmedWBPerson2987
RemarkTable S2Paper_evidenceWBPaper00040284
Curator_confirmedWBPerson2987
WBPhenotype:0002193Paper_evidenceWBPaper00044058
Curator_confirmedWBPerson2987
Remark"No allele of egl-17, egl-15 or any other downstream FGF component other than sem-5 had any effect on orientation as single mutants (Table 1), which is probably due to the involvement of sem-5 in one of the other pathways controlling vulval orientation as well as its role in the FGF pathway."Paper_evidenceWBPaper00044058
Curator_confirmedWBPerson2987
EQ_annotationsAnatomy_termWBbt:0006895PATO:0000460Paper_evidenceWBPaper00044058
Curator_confirmedWBPerson2987
ReferenceWBPaper00040284
WBPaper00006107
WBPaper00002741
WBPaper00006119
WBPaper00010221
WBPaper00044058
RemarkThis deletion removes 531bp towards the 5' end of egl-17. Exon 2 is completely removed along with nearly the whole of intron 2. The exact breakpoint are not published.Paper_evidenceWBPaper00002741
MethodDeletion_allele