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WormBase Tree Display for Variation: WBVar00089865

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WBVar00089865	Name	Public_name	n989
	Sequence_details	SeqStatus	Pending_curation
	Variation_type	Allele
	Origin	Species	Caenorhabditis elegans
		Laboratory	MT
		Status	Live
	Affects	Gene	WBGene00001174
	Description	Phenotype	WBPhenotype:0000006	Paper_evidence	WBPaper00001133
					WBPaper00001105
				Curator_confirmed	WBPerson2021
				Remark	egl-5 hermaphrodites either lack or have misplaced HSNs	Paper_evidence	WBPaper00001133
						Curator_confirmed	WBPerson2021
				Penetrance	High		Paper_evidence	WBPaper00001133
								WBPaper00001105
							Curator_confirmed	WBPerson2021
					Range	98	98	Paper_evidence	WBPaper00001133
									WBPaper00001105
								Curator_confirmed	WBPerson2021
				Recessive	Paper_evidence	WBPaper00001133
					Curator_confirmed	WBPerson2021
				EQ_annotations	Life_stage	WBls:0000057	PATO:0000460	Paper_evidence	WBPaper00001133
									WBPaper00001105
								Curator_confirmed	WBPerson2021
				Phenotype_assay	Temperature	20	Paper_evidence	WBPaper00001133
							Curator_confirmed	WBPerson2021
			WBPhenotype:0000070	Paper_evidence	WBPaper00001133
				Curator_confirmed	WBPerson2021
				Recessive	Paper_evidence	WBPaper00001133
					Curator_confirmed	WBPerson2021
				EQ_annotations	Life_stage	WBls:0000056	PATO:0000460	Paper_evidence	WBPaper00001133
								Curator_confirmed	WBPerson2021
				Phenotype_assay	Genotype	him-5(e1490)	Paper_evidence	WBPaper00001133
							Curator_confirmed	WBPerson2021
			WBPhenotype:0000154	Paper_evidence	WBPaper00001133
				Curator_confirmed	WBPerson2021
				Remark	Mutants show a 49 percent drop in brood size (compared to wild-type)	Paper_evidence	WBPaper00001133
						Curator_confirmed	WBPerson2021
				Recessive	Paper_evidence	WBPaper00001133
					Curator_confirmed	WBPerson2021
				EQ_annotations	Life_stage	WBls:0000057	PATO:0000460	Paper_evidence	WBPaper00001133
								Curator_confirmed	WBPerson2021
				Phenotype_assay	Temperature	20	Paper_evidence	WBPaper00001133
							Curator_confirmed	WBPerson2021
			WBPhenotype:0000316	Paper_evidence	WBPaper00001133
				Curator_confirmed	WBPerson2021
				Remark	Authors comment Occasional animals show some sensitivity to gentle touch	Paper_evidence	WBPaper00001133
						Curator_confirmed	WBPerson2021
				Recessive	Paper_evidence	WBPaper00001133
					Curator_confirmed	WBPerson2021
			WBPhenotype:0000354	Paper_evidence	WBPaper00001105
				Curator_confirmed	WBPerson2021
				Remark	HSN maturation is abnormal. No hood formation and nucleolar growth is observed	Paper_evidence	WBPaper00001105
						Curator_confirmed	WBPerson2021
				EQ_annotations	Anatomy_term	WBbt:0006830	PATO:0000460	Paper_evidence	WBPaper00001105
								Curator_confirmed	WBPerson2021
					Life_stage	WBls:0000038	PATO:0000460	Paper_evidence	WBPaper00001105
								Curator_confirmed	WBPerson2021
			WBPhenotype:0000425	Paper_evidence	WBPaper00001105
				Curator_confirmed	WBPerson2021
				Remark	Serotonin levels are reduced in HSNs (determined immunocytochemically).	Paper_evidence	WBPaper00001105
						Curator_confirmed	WBPerson2021
				EQ_annotations	Anatomy_term	WBbt:0006830	PATO:0000460	Paper_evidence	WBPaper00001105
								Curator_confirmed	WBPerson2021
					Life_stage	WBls:0000057	PATO:0000460	Paper_evidence	WBPaper00001105
								Curator_confirmed	WBPerson2021
			WBPhenotype:0000470	Paper_evidence	WBPaper00001105
				Curator_confirmed	WBPerson2021
				Remark	HSNs fail to arrive at their final destination (between P5/6 and V4)	Paper_evidence	WBPaper00001105
						Curator_confirmed	WBPerson2021
				EQ_annotations	Anatomy_term	WBbt:0006830	PATO:0000460	Paper_evidence	WBPaper00001105
								Curator_confirmed	WBPerson2021
					Life_stage	WBls:0000024	PATO:0000460	Paper_evidence	WBPaper00001105
								Curator_confirmed	WBPerson2021
			WBPhenotype:0000565	Paper_evidence	WBPaper00001133
				Curator_confirmed	WBPerson2021
				Recessive	Paper_evidence	WBPaper00001133
					Curator_confirmed	WBPerson2021
			WBPhenotype:0001340	Paper_evidence	WBPaper00001133
				Curator_confirmed	WBPerson2021
				Remark	See Table 1	Paper_evidence	WBPaper00001133
						Curator_confirmed	WBPerson2021
				Penetrance	Complete		Paper_evidence	WBPaper00001133
							Curator_confirmed	WBPerson2021
					Range	100	100	Paper_evidence	WBPaper00001133
								Curator_confirmed	WBPerson2021
				Recessive	Paper_evidence	WBPaper00001133
					Curator_confirmed	WBPerson2021
				EQ_annotations	Life_stage	WBls:0000057	PATO:0000460	Paper_evidence	WBPaper00001133
								Curator_confirmed	WBPerson2021
				Phenotype_assay	Treatment	0.75 mg/ml imipramine	Paper_evidence	WBPaper00001133
							Curator_confirmed	WBPerson2021
					Temperature	24	Paper_evidence	WBPaper00001133
							Curator_confirmed	WBPerson2021
			WBPhenotype:0001414	Paper_evidence	WBPaper00001133
				Curator_confirmed	WBPerson2021
				Remark	male mating is completely abolished	Paper_evidence	WBPaper00001133
						Curator_confirmed	WBPerson2021
				Penetrance	High		Paper_evidence	WBPaper00001133
							Curator_confirmed	WBPerson2021
				Recessive	Paper_evidence	WBPaper00001133
					Curator_confirmed	WBPerson2021
				EQ_annotations	Life_stage	WBls:0000056	PATO:0000460	Paper_evidence	WBPaper00001133
								Curator_confirmed	WBPerson2021
				Phenotype_assay	Genotype	him-5(e1490)	Paper_evidence	WBPaper00001133
							Curator_confirmed	WBPerson2021
		Phenotype_not_observed	WBPhenotype:0001068	Paper_evidence	WBPaper00001133
				Curator_confirmed	WBPerson2021
				Recessive	Paper_evidence	WBPaper00001133
					Curator_confirmed	WBPerson2021
				EQ_annotations	Life_stage	WBls:0000057	PATO:0000460	Paper_evidence	WBPaper00001133
								Curator_confirmed	WBPerson2021
				Phenotype_assay	Treatment	7.5 mg/ml serotonin	Paper_evidence	WBPaper00001133
							Curator_confirmed	WBPerson2021
					Temperature	24	Paper_evidence	WBPaper00001133
							Curator_confirmed	WBPerson2021
	Reference	WBPaper00014215
		WBPaper00001105
		WBPaper00001133
	Method	Allele