WormBase Tree Display for Variation: WBVar00089736

WBVar00089736 Evidence: Paper_evidence: WBPaper00032289
  Name: Public_name: n765
    Other_name: CE15381:p.Pro208LysfsTer16
      ZK662.4.2:c.622_812del
      ZK662.4.1:c.622_812del
    HGVSg: CHROMOSOME_X:g.15727663_15727853del
  Sequence_details: SMap: S_parent: Sequence: ZK678
    Flanking_sequences: TCAAATGTCAAGTTTACGAACATTGTGTGT AAGGTAAATTTAGCGTTTTTAACCTTTATA
    Mapping_target: ZK678
    Type_of_mutation: Insertion
      Deletion
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain (179)
    Laboratory: MT
      NM
      CX
    Status: Live
  Affects: Gene: WBGene00003004
      WBGene00023498
      WBGene00023497
    Transcript: ZK662.4.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: ZK662.4.1:c.622_812del
        HGVSp: CE15381:p.Pro208LysfsTer16
        cDNA_position: 628-818
        CDS_position: 622-812
        Protein_position: 208-271
        Exon_number: 4/10
        Codon_change: CCAAACGAAGAGATTTGCAAGCTGGTTGAAGAGAGTGCAGTTGTCAAACGATACAACGTTTGCTTCTACAACTACGTTACCCGTTTTGTGGCCGATTTGATGGAAATTGAAGAGTTTTCCAGTGGGCTGACACAATTGCGAACATTTGTTCGTTATATGAAACAAAATTCGGATATGTATAGCAAATTTAGa/a
        Amino_acid_change: PNEEICKLVEESAVVKRYNVCFYNYVTRFVADLMEIEEFSSGLTQLRTFVRYMKQNSDMYSKFR/X
      ZK662.4.2 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: ZK662.4.2:c.622_812del
        HGVSp: CE15381:p.Pro208LysfsTer16
        cDNA_position: 634-824
        CDS_position: 622-812
        Protein_position: 208-271
        Exon_number: 4/11
        Codon_change: CCAAACGAAGAGATTTGCAAGCTGGTTGAAGAGAGTGCAGTTGTCAAACGATACAACGTTTGCTTCTACAACTACGTTACCCGTTTTGTGGCCGATTTGATGGAAATTGAAGAGTTTTCCAGTGGGCTGACACAATTGCGAACATTTGTTCGTTATATGAAACAAAATTCGGATATGTATAGCAAATTTAGa/a
        Amino_acid_change: PNEEICKLVEESAVVKRYNVCFYNYVTRFVADLMEIEEFSSGLTQLRTFVRYMKQNSDMYSKFR/X
    Interactor (64)
  Genetics: Interpolated_map_position: X 22.945
    Mapping_data: In_2_point: 4457
        4458
        7082
      In_multi_point (19)
      In_pos_neg_data: 4461
  Description: Phenotype (8)
    Phenotype_not_observed: WBPhenotype:0000698 Paper_evidence: WBPaper00026863
          WBPaper00005344
        Curator_confirmed: WBPerson712
          WBPerson2987
        Remark: 0% animals (n=24) are aberrant in induction of VPCs as scored by Nomarski optics. Paper_evidence: WBPaper00026863
            Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: Paper_evidence: WBPaper00026863
              Curator_confirmed: WBPerson712
        Phenotype_assay: Temperature: 20 Paper_evidence: WBPaper00026863
              Curator_confirmed: WBPerson712
  Reference (26)
  Remark: Manually curated Gene associations preserved as a text remark so that VEP is the canonical predictor of consequence: WBGene00023498 WBGene00003004 Genomic_neighbourhood
  Method: Deletion_and_insertion_allele