WormBase Tree Display for Variation: WBVar00088574

WBVar00088574 Evidence: Paper_evidence: WBPaper00003977
  Name: Public_name: m86
    Other_name: CE02205:p.Arg88Ter
      F33H1.1e.1:c.262C>T
      CE43609:p.Arg111Ter
      F33H1.1c.1:c.214C>T
      F33H1.1a.1:c.688C>T
      F33H1.1b.1:c.763C>T
      CE17763:p.Arg230Ter
      CE01567:p.Arg72Ter
      F33H1.1d.1:c.331C>T
      CE28019:p.Arg255Ter
    HGVSg: CHROMOSOME_II:g.10160814G>A
  Sequence_details: SMap: S_parent: Sequence: F33H1
    Flanking_sequences: gcagactcgatcaacttgccgaacaatcaa gagcttcccccgcaacggtatgaataaaac
    Mapping_target: F33H1
    Type_of_mutation: Substitution: c t Paper_evidence: WBPaper00003977
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain (34)
    Laboratory: DR
      JT
      NFB
    Status: Live
  Affects: Gene: WBGene00000914
    Transcript (5)
    Interactor: WBInteraction000500067
      WBInteraction000501337
      WBInteraction000501338
      WBInteraction000501631
      WBInteraction000501852
      WBInteraction000501880
      WBInteraction000502038
      WBInteraction000502052
      WBInteraction000502053
      WBInteraction000502054
      WBInteraction000502055
      WBInteraction000502056
      WBInteraction000502057
      WBInteraction000502058
      WBInteraction000502059
      WBInteraction000502131
      WBInteraction000502419
      WBInteraction000502421
      WBInteraction000502610
      WBInteraction000502912
      WBInteraction000503479
      WBInteraction000503480
      WBInteraction000503538
      WBInteraction000503539
      WBInteraction000503540
      WBInteraction000503806
      WBInteraction000503807
      WBInteraction000503808
      WBInteraction000503809
      WBInteraction000503810
      WBInteraction000504827
      WBInteraction000504953
      WBInteraction000504954
      WBInteraction000504955
      WBInteraction000504956
      WBInteraction000504957
      WBInteraction000504958
      WBInteraction000504959
      WBInteraction000504960
      WBInteraction000504961
      WBInteraction000504962
      WBInteraction000504963
      WBInteraction000505104
      WBInteraction000505123
      WBInteraction000519830
      WBInteraction000519831
      WBInteraction000524548
      WBInteraction000541732
      WBInteraction000542217
      WBInteraction000542218
      WBInteraction000542219
      WBInteraction000556041
      WBInteraction000556042
      WBInteraction000556043
  Genetics: Interpolated_map_position: II 2.13278
    Mapping_data: In_2_point: 444
        769
        3381
      In_multi_point: 338
        961
        1558
      In_pos_neg_data: 4206
        4207
        4208
        4209
        4210
        4211
        4537
  Description: Phenotype (19)
    Phenotype_not_observed: WBPhenotype:0000039 Paper_evidence: WBPaper00002149
        Curator_confirmed: WBPerson712
        Remark: Adult lifespan was not increased. Animals were allowed to progress through development at 15 degrees C. then shifted to 25.5 degrees C. to determine lifespan. Paper_evidence: WBPaper00002149
            Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: Animals were raised at 15C and placed at 25.5C as L4 larvae or young adults for the life span assay. Paper_evidence: WBPaper00002149
              Curator_confirmed: WBPerson712
          Temperature: 25.5C Paper_evidence: WBPaper00002149
              Curator_confirmed: WBPerson712
      WBPhenotype:0000315 Paper_evidence: WBPaper00002149
        Curator_confirmed: WBPerson712
      WBPhenotype:0000436 Paper_evidence: WBPaper00035062
        Curator_confirmed: WBPerson2021
        Remark: In daf-19(m86) mutants, HYLS-1 localization was unaffected Paper_evidence: WBPaper00035062
            Curator_confirmed: WBPerson2021
      WBPhenotype:0000478 Paper_evidence: WBPaper00002149
        Curator_confirmed: WBPerson712
      WBPhenotype:0000882 Paper_evidence: WBPaper00003977
        Curator_confirmed: WBPerson641
        Remark: Table 2, Figure1; concerns the microvilli at the dendritic tips of the thermosensory AFD neurons Paper_evidence: WBPaper00003977
            Curator_confirmed: WBPerson641
        EQ_annotations: Anatomy_term: WBbt:0005662 PATO:0000460 Paper_evidence: WBPaper00003977
                Curator_confirmed: WBPerson641
          GO_term: GO:0005902 PATO:0000460 Paper_evidence: WBPaper00003977
                Curator_confirmed: WBPerson641
            GO:0030425 PATO:0000460 Paper_evidence: WBPaper00003977
                Curator_confirmed: WBPerson641
      WBPhenotype:0001530 Paper_evidence: WBPaper00000932
        Curator_confirmed: WBPerson712
        Remark: CEP does not stain with FITC at permissive or non-permissive temperatures. Paper_evidence: WBPaper00000932
            Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0005107 PATO:0000460 Paper_evidence: WBPaper00000932
                Curator_confirmed: WBPerson712
        Phenotype_assay: Temperature: 15C, 25C Paper_evidence: WBPaper00000932
              Curator_confirmed: WBPerson712
      WBPhenotype:0001535 Paper_evidence: WBPaper00002149
        Curator_confirmed: WBPerson712
        Remark: No FITC staining of ADE or PDE. Paper_evidence: WBPaper00002149
            Curator_confirmed: WBPerson712
      WBPhenotype:0001660 Paper_evidence: WBPaper00006052
        Curator_confirmed: WBPerson2021
        Remark: No disruption of ASE asymmetry (as seen with lim-6 reporters) Paper_evidence: WBPaper00006052
            Curator_confirmed: WBPerson2021
        Phenotype_assay: Genotype: otIs114, otIs6 Paper_evidence: WBPaper00006052
              Curator_confirmed: WBPerson2021
  Reference (24)
  Remark
  Method: Substitution_allele