WormBase Tree Display for Variation: WBVar00087751

WBVar00087751 Evidence: Paper_evidence: WBPaper00000495
  Name: Public_name: hc23
  Sequence_details: SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00000365
    Laboratory: BA
    Status: Live
  Affects: Gene: WBGene00001418
  Genetics: Mapping_data: In_multi_point: 217
        1064
      In_pos_neg_data: 1603
  Description: Phenotype: WBPhenotype:0000284 Paper_evidence: WBPaper00000495
        Curator_confirmed: WBPerson712
        Remark: Males were never observed to transfer sperm. Paper_evidence: WBPaper00000495
            Curator_confirmed: WBPerson712
        Penetrance: Incomplete: Paper_evidence: WBPaper00000495
              Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: 25 Paper_evidence: WBPaper00000495
              Curator_confirmed: WBPerson712
      WBPhenotype:0000357 Paper_evidence: WBPaper00000495
        Curator_confirmed: WBPerson712
        Remark: At the permissive temperature, ts mutants produced 100 to 300 progeny and less than 65 unfertilized eggs, which were laid late in the life cycle, like those of wild-type hermaphrodites. At the restrictive temperature of 25 deg C, animals produced only a few progeny and laid 72 to 282 unfertilized eggs. Paper_evidence: WBPaper00000495
            Curator_confirmed: WBPerson712
        Penetrance: Incomplete: Paper_evidence: WBPaper00000495
              Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: 25 Paper_evidence: WBPaper00000495
              Curator_confirmed: WBPerson712
      WBPhenotype:0000688 Paper_evidence: WBPaper00000495
        Curator_confirmed: WBPerson712
        Remark: At the permissive temperature, ts mutants produced 100 to 300 progeny and less than 65 unfertilized eggs, which were laid late in the life cycle, like those of wild-type hermaphrodites. At the restrictive temperature of 25 deg C, animals produced only a few progeny and laid 72 to 282 unfertilized eggs. BA23 hermaphrodites produce many fewer oocytes at 25" than at 16". Paper_evidence: WBPaper00000495
            Curator_confirmed: WBPerson712
        Penetrance: Incomplete: Paper_evidence: WBPaper00000495
              Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: 25 Paper_evidence: WBPaper00000495
              Curator_confirmed: WBPerson712
      WBPhenotype:0000693 Paper_evidence: WBPaper00000495
        Curator_confirmed: WBPerson712
        Penetrance: Incomplete: Paper_evidence: WBPaper00000495
              Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: 25 Paper_evidence: WBPaper00000495
              Curator_confirmed: WBPerson712
      WBPhenotype:0000806 Paper_evidence: WBPaper00000495
        Curator_confirmed: WBPerson712
        Remark: Animals are fertilization defective. Animals have a short (5-10 hrs) temperature sensitive period (TSP) late in their development. Paper_evidence: WBPaper00000495
            Curator_confirmed: WBPerson712
        Penetrance: Incomplete: Paper_evidence: WBPaper00000495
              Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: 25 Paper_evidence: WBPaper00000495
              Curator_confirmed: WBPerson712
      WBPhenotype:0000863 Paper_evidence: WBPaper00000495
        Curator_confirmed: WBPerson712
        Remark: Males are ts sterile, producing less progeny at restrictive temperatures. Paper_evidence: WBPaper00000495
            Curator_confirmed: WBPerson712
          Mating of fertile dpy-11 hermaphrodites with sterile fer males did not reduce hermaphrodite self-fertilization, whereas mating with wild-type males or with permissively grown males, did. Paper_evidence: WBPaper00000495
            Curator_confirmed: WBPerson712
        Penetrance: Incomplete: Paper_evidence: WBPaper00000495
              Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: 25 Paper_evidence: WBPaper00000495
              Curator_confirmed: WBPerson712
      WBPhenotype:0001720 Paper_evidence: WBPaper00000495
        Curator_confirmed: WBPerson712
        Remark: Nonfunctional sperm of fer hermaphrodites are progressively lost fro the spermathecae of mutant hermaphrodites. by the time 40-70 oocytes have passed through the spermathecae of sterile hermaphrodites, most of the sperm have been swept out rather than migrating back through the spermathecal valve. Paper_evidence: WBPaper00000495
            Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: 25 Paper_evidence: WBPaper00000495
              Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0000033 Paper_evidence: WBPaper00000495
        Curator_confirmed: WBPerson712
        Remark: Animals grow and develop at the same rate as wild type, initiating egg laying at 45 hr post-hatching, as do N2 hermaphrodites. Paper_evidence: WBPaper00000495
            Curator_confirmed: WBPerson712
      WBPhenotype:0000186 Paper_evidence: WBPaper00000495
        Curator_confirmed: WBPerson712
        Remark: Oocytes are produced and are capable of being fertilized. Paper_evidence: WBPaper00000495
            Curator_confirmed: WBPerson712
      WBPhenotype:0000670 Paper_evidence: WBPaper00000495
        Curator_confirmed: WBPerson712
        Remark: At the start of their egg-laying period, 45 hr post-hatching at 25 deg C, the spermathecae of these hermaphrodites contain over 170 sperm. Paper_evidence: WBPaper00000495
            Curator_confirmed: WBPerson712
      WBPhenotype:0000676 Paper_evidence: WBPaper00000495
        Curator_confirmed: WBPerson712
        Remark: Animals grow and develop at the same rate as wild type, initiating egg laying at 45 hr post-hatching, as do N2 hermaphrodites. Paper_evidence: WBPaper00000495
            Curator_confirmed: WBPerson712
  Reference: WBPaper00000495
  Method: Allele