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WormBase Tree Display for Variation: WBVar00087743

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Name Class

WBVar00087743EvidencePaper_evidenceWBPaper00000495
NamePublic_namehc2
Sequence_detailsSeqStatusPending_curation
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00000358
WBStrain00000371
LaboratoryBA
StatusLive
AffectsGeneWBGene00001415
GeneticsMapping_dataIn_multi_point223
1252
1635
3112
In_pos_neg_data5731
5740
5948
DescriptionPhenotypeWBPhenotype:0000357Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
RemarkAt the permissive temperature, ts mutants produced 100 to 300 progeny and less than 65 unfertilized eggs, which were laid late in the life cycle, like those of wild-type hermaphrodites. At the restrictive temperature of 25 deg C, animals produced only a few progeny and laid 72 to 282 unfertilized eggs.Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
PenetranceIncompletePaper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitive25Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
WBPhenotype:0000387Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Remarkhermaphrodites and males grown at 25C produce nonfunctional nonmotile sperm with aberrant pseudopods, perinuclear tubules. TSP L2-L4.Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitivePerson_evidenceWBPerson261
Curator_confirmedWBPerson712
Ease_of_scoringES2_Difficult_to_scorePerson_evidenceWBPerson261
Curator_confirmedWBPerson712
WBPhenotype:0000688Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
RemarkAt the permissive temperature, ts mutants produced 100 to 300 progeny and less than 65 unfertilized eggs, which were laid late in the life cycle, like those of wild-type hermaphrodites. At the restrictive temperature of 25 deg C, animals produced only a few progeny and laid 72 to 282 unfertilized eggs.Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
PenetranceIncompletePaper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitive25Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
WBPhenotype:0000693Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
PenetranceIncompletePaper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitive25Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
WBPhenotype:0000806Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
RemarkAnimals are fertilization defective. Animals have a long (24 hr) temperature sensitive period (TSP).Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
PenetranceIncompletePaper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitive25Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
WBPhenotype:0000863Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
RemarkMales are strong ts sterile, producing less progeny at restrictive and permissive temperatures than other fer males.Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
Mating of fertile dpy-11 hermaphrodites with sterile fer males did not reduce hermaphrodite self-fertilization.Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
PenetranceIncompletePaper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitive25Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
WBPhenotype:0001386Person_evidenceWBPerson261
Curator_confirmedWBPerson712
RemarkSelf fertility 2% (25C) 70% (16C).Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitivePerson_evidenceWBPerson261
Curator_confirmedWBPerson712
WBPhenotype:0001720Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
RemarkNonfunctional sperm of fer hermaphrodites are progressively lost fro the spermathecae of mutant hermaphrodites. by the time 40-70 oocytes have passed through the spermathecae of sterile hermaphrodites, most of the sperm have been swept out rather than migrating back through the spermathecal valve.Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitive25Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
Phenotype_not_observedWBPhenotype:0000033Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
RemarkAnimals grow and develop at the same rate as wild type, initiating egg laying at 45 hr post-hatching, as do N2 hermaphrodites.Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
WBPhenotype:0000186Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
RemarkOocytes are produced and are capable of being fertilized.Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
WBPhenotype:0000284Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
RemarkSperm were transferred during copulation.Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
PenetranceIncompletePaper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitive25Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
WBPhenotype:0000670Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
RemarkAt the start of their egg-laying period, 45 hr post-hatching at 25 deg C, the spermathecae of these hermaphrodites contain over 170 sperm.Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
WBPhenotype:0000676Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
RemarkAnimals grow and develop at the same rate as wild type, initiating egg laying at 45 hr post-hatching, as do N2 hermaphrodites.Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
ReferenceWBPaper00000495
MethodAllele