WormBase Tree Display for Variation: WBVar00054407

WBVar00054407 Evidence: Paper_evidence: WBPaper00025116
  Name: Public_name: ct42
    Other_name: CE51690:p.Gly1608Glu
      CE23997:p.Gly2540Glu
      T21E12.4a.1:c.7619G>A
      T21E12.4b.1:c.4823G>A
    HGVSg: CHROMOSOME_I:g.4395350G>A
  Sequence_details: SMap: S_parent: Sequence: T21E12
    Flanking_sequences: acaaaccattggttctgtgtggtcctccgg atctggtaaaactatgactcttctcgctgc
    Mapping_target: T21E12
    Type_of_mutation: Substitution: g a Paper_evidence: WBPaper00025116
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00008442
    Laboratory: BW
    Status: Live
  Affects: Gene: WBGene00000962
    Transcript: T21E12.4a.1 (12)
      T21E12.4b.1 (12)
  Genetics: Interpolated_map_position: I -1.3103
    Mapping_data: In_multi_point: 1758
        1759
  Description: Phenotype: WBPhenotype:0000050 Paper_evidence: WBPaper00001274
        Curator_confirmed: WBPerson399
        Penetrance: Complete: Paper_evidence: WBPaper00001274
              Curator_confirmed: WBPerson399
        Dominant: Paper_evidence: WBPaper00001274
          Curator_confirmed: WBPerson399
        Temperature_sensitive: Heat_sensitive: Paper_evidence: WBPaper00001274
              Curator_confirmed: WBPerson399
        Phenotype_assay: Control_strain: WBStrain00000001 Paper_evidence: WBPaper00001274
              Curator_confirmed: WBPerson399
      WBPhenotype:0000052 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: dominant embryonic Mel Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Dominant: Person_evidence: WBPerson261
          Curator_confirmed: WBPerson712
      WBPhenotype:0000057 Paper_evidence: WBPaper00001274
        Curator_confirmed: WBPerson399
        Penetrance: Complete: Paper_evidence: WBPaper00001274
              Curator_confirmed: WBPerson399
        Recessive: Paper_evidence: WBPaper00001274
          Curator_confirmed: WBPerson399
        Temperature_sensitive: Heat_sensitive: Paper_evidence: WBPaper00001274
              Curator_confirmed: WBPerson399
        Phenotype_assay: Control_strain: WBStrain00000001 Paper_evidence: WBPaper00001274
              Curator_confirmed: WBPerson399
      WBPhenotype:0000070 Paper_evidence: WBPaper00001274
        Curator_confirmed: WBPerson399
        Penetrance: Complete: Paper_evidence: WBPaper00001274
              Curator_confirmed: WBPerson399
        Dominant: Paper_evidence: WBPaper00001274
          Curator_confirmed: WBPerson399
        Temperature_sensitive: Heat_sensitive: Paper_evidence: WBPaper00001274
              Curator_confirmed: WBPerson399
        Phenotype_assay: Control_strain: WBStrain00000001 Paper_evidence: WBPaper00001274
              Curator_confirmed: WBPerson399
      WBPhenotype:0000675 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: recessive zygotic larval lethality Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Recessive: Person_evidence: WBPerson261
          Curator_confirmed: WBPerson712
      WBPhenotype:0001018 Paper_evidence: WBPaper00024189
        Curator_confirmed: WBPerson712
        Remark: By shifting to nonpermissive temperature, large cells with cytokinesis defects were produced. Paper_evidence: WBPaper00024189
            Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: Paper_evidence: WBPaper00024189
              Curator_confirmed: WBPerson712
      WBPhenotype:0001566 Paper_evidence: WBPaper00024189
        Curator_confirmed: WBPerson712
        Remark: By shifting to nonpermissive temperature, aberrant embryonic enclosure was produced. Paper_evidence: WBPaper00024189
            Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: Paper_evidence: WBPaper00024189
              Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0001748 Paper_evidence: WBPaper00024189
        Curator_confirmed: WBPerson712
        Remark: Pharynx is attached as monitored under light microscope or by MH27 antibody staining or CeAJs (data not shown). Even after shifts to a nonpermissive temperature. Paper_evidence: WBPaper00024189
            Curator_confirmed: WBPerson712
  Reference: WBPaper00024189
    WBPaper00001274
    WBPaper00016486
  Method: Substitution_allele