WormBase Tree Display for Variation: WBVar00000407

WBVar00000407 Name: Public_name: b404
  Sequence_details: Mapping_target: Y110A7A
    Type_of_mutation: Deletion
    SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00005819
    Laboratory: DH
    Status: Live
  Affects: Gene: WBGene00006797
  Isolation: Mutagen: EMS Paper_evidence: WBPaper00024268
  Description: Phenotype: WBPhenotype:0000017 Paper_evidence: WBPaper00000484
        Person_evidence: WBPerson261
        Curator_confirmed: WBPerson2021
          WBPerson712
        Affected_by: Molecule: WBMol:00003650 Paper_evidence: WBPaper00000484
              Person_evidence: WBPerson261
              Curator_confirmed: WBPerson2021
                WBPerson712
        Phenotype_assay: Treatment: 2mM aldicarb Paper_evidence: WBPaper00000484
              Curator_confirmed: WBPerson2021
      WBPhenotype:0000039 Paper_evidence: WBPaper00040570
        Curator_confirmed: WBPerson8126
        Remark: Fig.6 (lifespan extension upon reserpine treatment, not different from wild type) Paper_evidence: WBPaper00040570
            Curator_confirmed: WBPerson8126
        Affected_by: Molecule: WBMol:00002955 Paper_evidence: WBPaper00040570
              Curator_confirmed: WBPerson8126
      WBPhenotype:0000421 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: slight Lev Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00004019 Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
      WBPhenotype:0000643 Paper_evidence: WBPaper00000484
        Person_evidence: WBPerson261
        Curator_confirmed: WBPerson2021
          WBPerson712
        Remark: slight Unc Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0001289 Paper_evidence: WBPaper00000484
        Person_evidence: WBPerson261
        Curator_confirmed: WBPerson2021
          WBPerson712
        Remark: Animals are resistant to the acetylcholinesterase inhibitors trichlorfon and eserine. Paper_evidence: WBPaper00000484
            Curator_confirmed: WBPerson2021
          trichlorfon resistant Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00002865 Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: 1mM trichlorfon. 1mM eserine Paper_evidence: WBPaper00000484
              Curator_confirmed: WBPerson2021
    Phenotype_not_observed: WBPhenotype:0000421 Paper_evidence: WBPaper00000484
        Curator_confirmed: WBPerson2021
        Affected_by: Molecule: WBMol:00004019 Paper_evidence: WBPaper00000484
              Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: 1mM levamisole Paper_evidence: WBPaper00000484
              Curator_confirmed: WBPerson2021
      WBPhenotype:0001578 Paper_evidence: WBPaper00000484
        Curator_confirmed: WBPerson2021
        Remark: Animals are not resistant to the cholinergic agonist carbachol. Paper_evidence: WBPaper00000484
            Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: 1mM carbachol Paper_evidence: WBPaper00000484
              Curator_confirmed: WBPerson2021
  Reference: WBPaper00040570
    WBPaper00000484
    WBPaper00018321
    WBPaper00023610
  Remark: Deletion completely removes exon 7 Paper_evidence: WBPaper00024268
  Method: Deletion_allele