WormBase Tree Display for Variation: WBVar00000141
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| WBVar00000141 | Evidence | Paper_evidence | WBPaper00031911 | |||||
|---|---|---|---|---|---|---|---|---|
| Name | Public_name | am134 | ||||||
| Other_name | T23B12.4.1:c.2071C>T | |||||||
| CE29351:p.Arg691Ter | ||||||||
| HGVSg | CHROMOSOME_V:g.8464780C>T | |||||||
| Sequence_details | SMap | S_parent | Sequence | T23B12 | ||||
| Flanking_sequences | gatgatgctgaaaaactaagattcgaaaga | gattcgaaccattcgactcacttgggcctc | ||||||
| Mapping_target | T23B12 | |||||||
| Type_of_mutation | Substitution | c | t | Paper_evidence | WBPaper00045887 | |||
| SeqStatus | Sequenced | |||||||
| Variation_type | Allele | |||||||
| Origin | Species | Caenorhabditis elegans | ||||||
| Strain | WBStrain00040584 | |||||||
| Laboratory | WU | |||||||
| Status | Live | |||||||
| Affects | Gene | WBGene00020719 | ||||||
| Transcript | T23B12.4.1 | VEP_consequence | stop_gained | |||||
| VEP_impact | HIGH | |||||||
| HGVSc | T23B12.4.1:c.2071C>T | |||||||
| HGVSp | CE29351:p.Arg691Ter | |||||||
| cDNA_position | 2112 | |||||||
| CDS_position | 2071 | |||||||
| Protein_position | 691 | |||||||
| Exon_number | 7/10 | |||||||
| Codon_change | Cga/Tga | |||||||
| Amino_acid_change | R/* | |||||||
| Genetics | Interpolated_map_position | V | 1.41201 | |||||
| Description | Phenotype | WBPhenotype:0001750 | Paper_evidence | WBPaper00031911 | ||||
| Curator_confirmed | WBPerson712 | |||||||
| Remark | Animals developed to adult stage on NAMM supplemental with 0.3mM or 0.22mM zinc, a concentration that causes almost 100% or 25%, respectively, of wild-type animals to arrest as L1 larvae. | Paper_evidence | WBPaper00031911 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| Semi_dominant | Paper_evidence | WBPaper00031911 | ||||||
| Curator_confirmed | WBPerson712 | |||||||
| Phenotype_assay | Treatment | Animals were cultured on Nobel agar minimal media (NAMM) with supplemental zinc sulfate starting at the egg stage, and development was monitored daily. | Paper_evidence | WBPaper00031911 | ||||
| Curator_confirmed | WBPerson712 | |||||||
| Temperature | 20 | Paper_evidence | WBPaper00031911 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| Phenotype_not_observed | WBPhenotype:0000043 | Paper_evidence | WBPaper00031911 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| WBPhenotype:0000154 | Paper_evidence | WBPaper00031911 | ||||||
| Curator_confirmed | WBPerson712 | |||||||
| WBPhenotype:0000520 | Paper_evidence | WBPaper00031911 | ||||||
| Curator_confirmed | WBPerson712 | |||||||
| WBPhenotype:0000648 | Paper_evidence | WBPaper00031911 | ||||||
| Curator_confirmed | WBPerson712 | |||||||
| WBPhenotype:0001206 | Paper_evidence | WBPaper00031911 | ||||||
| Curator_confirmed | WBPerson712 | |||||||
| Reference | WBPaper00031911 | |||||||
| WBPaper00045887 | ||||||||
| Method | Substitution_allele |
