WormBase Tree Display for Transgene: WBTransgene00009061
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| WBTransgene00009061 | Public_name | WBPaper00038510Is2 | |||||
|---|---|---|---|---|---|---|---|
| Summary | [Pbaf-1::LMN-1 (deletion K46)::GFP] | ||||||
| Synonym | WBPaper00038510_Is2 | ||||||
| Construction | Construct | WBCnstr00008749 | |||||
| Construction_summary | Deletion K46 lmn-1 was cloned into the pAD010 vector, which includes the baf-1 promoter (Margalit et al., 2007), the unc-119 gene, and a gfp gene with C. elegans introns. | ||||||
| Genetic_information | Integrated | ||||||
| Phenotype | WBPhenotype:0000926 | Paper_evidence | WBPaper00038510 | ||||
| Curator_confirmed | WBPerson712 | ||||||
| Remark | In both lateral- and cross-thin sections of GFP:wt L4 worms, muscle cells were uniformly arranged, with sarcomeres containing even, parallel filaments (black arrows) clearly defined between dense bodies (white arrows) and cell-cell attachments, similar to wildtype animals. In GFP::deletion K46 animals, this organized pattern was severely disrupted. Also major disorganization is evident in the sub-cuticle region between the cuticle and the muscle fiber. | Paper_evidence | WBPaper00038510 | ||||
| Curator_confirmed | WBPerson712 | ||||||
| Caused_by_other | LMN-1 deletion K46 | Paper_evidence | WBPaper00038510 | ||||
| Curator_confirmed | WBPerson712 | ||||||
| Reference | WBPaper00038510 | ||||||
| Species | Caenorhabditis elegans |
