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WormBase Tree Display for Transgene: WBTransgene00008968

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Name Class

WBTransgene00008968Public_namehjIs28
Summary[hsp-16-41p::3xFLAG::EGL-4(K162N)::SL2::mCherry::C. briggsae unc-119(+)]
ConstructionConstructWBCnstr00008660
Coinjection_otherCbr-unc-119(+)
Integration_methodParticle_bombardment
Construction_summaryconstitutively active EGL-4.
Genetic_informationIntegrated
PhenotypeWBPhenotype:0000005Paper_evidenceWBPaper00038421
Curator_confirmedWBPerson712
RemarkAlthough no significant difference was observed in egg-laying behavior between wild-type animals and animals that expressed constitutively active (or kinase dead EGL-4 (hjIs30)), 2 hours after heat-shock when the expression level of ectopic EGL-4 peaked, elevated egg-laying was observed 24 hours after heat-shock.Paper_evidenceWBPaper00038421
Curator_confirmedWBPerson712
Caused_by_geneWBGene00001173Paper_evidenceWBPaper00038421
Curator_confirmedWBPerson712
WBPhenotype:0000662Paper_evidenceWBPaper00038421
Curator_confirmedWBPerson712
RemarkAlthough no significant difference was observed in foraging behavior between wild-type animals and animals that expressed constitutively active (or kinase dead EGL-4 (hjIs30)), 2 hours after heat-shock when the expression level of ectopic EGL-4 peaked, excessive dwelling was observed 24 hours after heat-shock. The excessive dwelling was comparable to that of egl-4(gf) mutant animals.Paper_evidenceWBPaper00038421
Curator_confirmedWBPerson712
Caused_by_geneWBGene00001173Paper_evidenceWBPaper00038421
Curator_confirmedWBPerson712
Used_forInteractorWBInteraction000501303
ReferenceWBPaper00038421
SpeciesCaenorhabditis elegans