WormBase Tree Display for Transgene: WBTransgene00005887
expand all nodes | collapse all nodes | view schema
WBTransgene00005887 | Public_name | qyIs15 | |||||
---|---|---|---|---|---|---|---|
Summary | [zmp-1p::HA beta-tail] | ||||||
Construction | Construct | WBCnstr00005755 | |||||
Construction_summary | A dominant negative form of the C. elegans integrin expressed in the anchor cell. | ||||||
Genetic_information | Integrated | ||||||
Map | IV | ||||||
Phenotype | WBPhenotype:0000104 | Paper_evidence | WBPaper00035117 | ||||
Curator_confirmed | WBPerson2021 | ||||||
Remark | As levels of HA-btail increased, UNC-40, HIM-4, MIG-2 and PI(4,5)P2 failed to further concentrate at the invasive cell membrane and there was a loss of F-actin polarity. PAR-3 and AJM-1 localized normally in HA-btail animals | Paper_evidence | WBPaper00035117 | ||||
Curator_confirmed | WBPerson2021 | ||||||
WBPhenotype:0001652 | Paper_evidence | WBPaper00035117 | |||||
Curator_confirmed | WBPerson2021 | ||||||
Remark | Complete block in invasion at the P6.p four-cell stage | Paper_evidence | WBPaper00035117 | ||||
Curator_confirmed | WBPerson2021 | ||||||
Phenotype_not_observed | WBPhenotype:0000717 | Paper_evidence | WBPaper00035117 | ||||
Curator_confirmed | WBPerson2021 | ||||||
Remark | Transcriptional reporters for FOS-1A and all of its known targets were expressed normally in HA-btail animals | Paper_evidence | WBPaper00035117 | ||||
Curator_confirmed | WBPerson2021 | ||||||
Reference | WBPaper00035117 | ||||||
WBPaper00038447 | |||||||
WBPaper00039950 | |||||||
WBPaper00044874 | |||||||
WBPaper00046146 | |||||||
WBPaper00050698 | |||||||
WBPaper00053373 | |||||||
Species | Caenorhabditis elegans |