WormBase Tree Display for Transgene: WBTransgene00001046
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| WBTransgene00001046 | Public_name | muIs49 | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Summary | [unc-22(+) egl-20::GFP] | ||||||||
| Synonym | [egl-20::gfp; unc-22 antisense] | ||||||||
| Construction | Construct | WBCnstr00001037 | |||||||
| Construction_summary | Rescuing egl-20::gfp translational fusion. The rescuing fusion (pJW31) was made by inserting an XmaI-digested fragment of gfp coding sequences (pPD113.37, a F64L S65T variant from A. Fire) into an AgeI site engineered after the last codon of egl-20. In addition to the entire egl-20 genomic sequence, this construct contains 6.8 kb upstream of the egl-20 start site and 1.9 kb downstream of the stop codon. | ||||||||
| Genetic_information | Integrated | ||||||||
| Map | V | ||||||||
| Map_evidence | Paper_evidence | WBPaper00031356 | |||||||
| Phenotype | WBPhenotype:0000470 | Paper_evidence | WBPaper00024898 | ||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| Remark | "In egl-20::gfp; vab-8 animals, the HSNs migrated excessively 59.3% of the time, a frequency much higher than that seen in vab-8 mutants alone (Figure 3; Table 1)." | Paper_evidence | WBPaper00024898 | ||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| Penetrance | Incomplete | Paper_evidence | WBPaper00024898 | ||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| Caused_by_gene | WBGene00001188 | Paper_evidence | WBPaper00024898 | ||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0006830 | PATO:0000460 | Paper_evidence | WBPaper00024898 | ||||
| Curator_confirmed | WBPerson2987 | ||||||||
| Life_stage | WBls:0000024 | PATO:0000460 | Paper_evidence | WBPaper00024898 | |||||
| Curator_confirmed | WBPerson2987 | ||||||||
| GO_term | GO:0016477 | PATO:0000460 | Paper_evidence | WBPaper00024898 | |||||
| Curator_confirmed | WBPerson2987 | ||||||||
| Phenotype_assay | Treatment | From Table 1 legend: "Because the HSNs were sometimes misplaced anteriorly and at other times were misplaced posteriorly, we present the data for both phenotypes. An HSN was scored as misplaced anteriorly if its nucleus was anterior to the P5/6 nucleus and as misplaced posteriorly if its nucleus was posterior to the V4 nucleus." | Paper_evidence | WBPaper00024898 | |||||
| Curator_confirmed | WBPerson2987 | ||||||||
| Used_for | Expr_pattern | Expr989 | |||||||
| Expr3846 | |||||||||
| Expr3848 | |||||||||
| Interactor | WBInteraction000538627 | ||||||||
| WBInteraction000538628 | |||||||||
| Associated_with | Strain | WBStrain00004841 | |||||||
| Reference (11) | |||||||||
| Species | Caenorhabditis elegans |
