WormBase Tree Display for Strain: WBStrain00054650
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| WBStrain00054650 | Genotype | drsh-1(viz43)/tmC18[dpy-5(tmIs1200[myo-2p::mVenus])] I. | ||
|---|---|---|---|---|
| Public_name | AUM1535 | |||
| Contains | Gene | WBGene00001067 | ||
| WBGene00003514 | ||||
| WBGene00009163 | ||||
| Rearrangement | tmC18 | |||
| Transgene | WBTransgene00024742 | |||
| Properties | Outcrossed | x5 | ||
| Mutagen | CRISPR_Cas9 | |||
| CGC_received | 16 Jun 2023 00:00:00 | |||
| Location | CGC | |||
| Remark | [D943G] substitution mutation in conserved residue within RNAse III domain. Balancer marked with myo-2p::Venus. Pick fertile wild-type (non-Dpy) Venus+ to maintain. drsh-1(viz43) homozygous animals display heterochronic phenotypes beginning at L3/L4 molt and typically burst at the vulva in L4. Heterozygotes are wild-type with pharyngeal Venus fluorescence, and segregate Venus+ heterozygotes, non-Venus viz-43 homozygotes, and Dpy Venus+ tmC18 homozygotes. Reference: Barish S, et al. Human Mol Genet. 2022 Aug 25;31(17):2934-2950. doi: 10.1093/hmg/ddac085. PMID: 35405010. | Inferred_automatically | From CGC strain data | |
| Made_by: J. H. Seemann | CGC_data_submission | |||
| Species | Caenorhabditis elegans |
