WormBase Tree Display for Strain: WBStrain00050604
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| WBStrain00050604 | Status | Live | ||
|---|---|---|---|---|
| Genotype | rab-5(udn14)/tmC18 [dpy-5(tmIs1200)] I. | |||
| Public_name | UDN100028 | |||
| Contains | Gene | WBGene00001067 | ||
| WBGene00004268 | ||||
| Rearrangement | tmC18 | |||
| Transgene | WBTransgene00024742 | |||
| Disease_info | Models_disease | DOID:3082 | ||
| Models_disease_in_annotation | WBDOannot00001154 | |||
| Properties | Outcrossed | x3 | ||
| Mutagen | CRISPR_Cas9 | |||
| CGC_received | 30 Mar 2022 00:00:00 | |||
| Location | UDN | |||
| CGC | ||||
| Remark | [2022-03-09T03:06:44.75Z WBPerson324] New Strain: rab-5(udn14)/tmC18[dpy5(tmIs1200[myo-2p::Venus])] I | Curator_confirmed | WBPerson324 | |
| [2022-03-09T03:28:46.878Z WBPerson324] Strain: WBPaper00062455; Genotype: rab-5(udn14)/tmC18[dpy5(tmIs1200[myo-2p::Venus])] I | Curator_confirmed | WBPerson324 | ||
| Must be maintained at 20 degrees. Homozygous lethal rab-5 [D135H] mutation balanced by tmC18. Balancer marked with myo-2p::Venus. Heterozygotes are WT with pharyngeal Venus fluorescence, and segregate Venus+ heterozygotes, non-Venus rab-5[D135H] homozygotes (L1 lethal), and Dpy Venus+ tmC18 homozygotes. Pick fertile wild-type Venus+ to maintain. Silent BstAPI site added in D135H for genotyping ease. Heterozygous rab-5[D135H] animals are small and have decreased locomotion. Reference: Huang et al. 2022. PMID: 35121658 | Inferred_automatically | From CGC strain data | ||
| Made_by: UDN Screening Center | CGC_data_submission | |||
| Reference | WBPaper00062455 | |||
| Species | Caenorhabditis elegans |
